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GAS6 抗体 (N-Term)

This anti-GAS6 antibody is a 兔 多克隆 antibody detecting GAS6 in WB, ELISA 和 IHC (p). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6992169
发货至: 中国

Quick Overview for GAS6 抗体 (N-Term) (ABIN6992169)

抗原

See all GAS6 抗体
GAS6 (Growth Arrest-Specific 6 (GAS6))

适用

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人, 小鼠, 大鼠

宿主

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  • 6
  • 2
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  • 1

克隆类型

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  • 2
多克隆

标记

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This GAS6 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 15
    • 6
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    • 2
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    AA 60-110, N-Term

    特异性

    GAS6 antibody is human, mouse and rat reactive. At least four isoforms of GAS6 are known to exist, this antibody will only detect the longest isoform.

    纯化方法

    GAS6 Antibody is affinity chromatography purified via peptide column.

    免疫原

    GAS6 antibody was raised against a 19 amino acid peptide from near the amino terminus of human GAS6. The immunogen is located within amino acids 60 - 110 of GAS6.

    亚型

    IgG
  • 应用备注

    GAS6 antibody can be used for the detection of GAS6 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL.

    Antibody validated: Western Blot in mouse samples and Immunohistochemistry in mouse samples. All other applications and species not yet tested.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    GAS6 Antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,4 °C

    储存方法

    GAS6 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
  • 抗原

    GAS6 (Growth Arrest-Specific 6 (GAS6))

    别名

    GAS6

    背景

    The growth arrest-specific 6 (GAS6) protein is a gamma-carboxyglutamic acid (Gla)-containing protein and a member of a family of plasma vitamin K-dependent proteins. GAS6 is involved in vascular homeostasis, cell proliferation, apoptosis, leukocyte migration, and platelet aggregation (1,2). GAS6 is the ligand for the type I transmembrane receptor tyrosine kinase receptors Tyro3, Axl, and Mer (3). This gene is frequently overexpressed in many cancers and has been implicated as an adverse prognostic marker (4). Elevated protein levels are additionally associated with a variety of disease states, including venous thromboembolic disease, systemic lupus erythematosus, chronic renal failure, and preeclampsia (2).

    分子量

    Predicted: 75 kDa

    Observed: 75 kDa

    基因ID

    2621

    NCBI登录号

    NP_000811

    UniProt

    Q14393

    途径

    RTK signaling, Carbohydrate Homeostasis, Production of Molecular Mediator of Immune Response
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