DEPDC1B 抗体 (C-Term)
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北京 101111
Quick Overview for DEPDC1B 抗体 (C-Term) (ABIN6992160)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- DEPDC1B antibody is human specific. At least two isoforms are known to exist, this antibody will only detect the largest isoform. DEPDC1B antibody is predicted to not cross-react with DEPDC1A.
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纯化方法
- DEPDC1B antibody is affinity chromatography purified via peptide column.
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免疫原
- DEPDC1B antibody was raised against a 19 amino acid peptide near the carboxy terminus of human DEPDC1B. The immunogen is located within the last 50 amino acids of DEPDC1B.
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亚型
- IgG
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anti-DEP Domain Containing 1B (DEPDC1B) (AA 343-529) antibody
DEPDC1B 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-DEP Domain Containing 1B (DEPDC1B) (AA 430-529) antibodyDEPDC1B 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2H2 unconjugated
anti-DEP Domain Containing 1B (DEPDC1B) (AA 87-136) antibodyDEPDC1B 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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DEPDC1B antibody can be used for detection of DEPDC1B by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL.
Antibody validated: Western Blot in human samples and Immunohistochemistry in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- DEPDC1B antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- DEPDC1B antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- DEPDC1B (DEP Domain Containing 1B (DEPDC1B))
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别名
- DEPDC1B
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背景
- The DEP domain-containing 1B (DEPDC1B) protein was initially identified as a radiation response biomarker in human lymphoblastoid cell lines (1). Like the related protein DEPDC1A, expression of DEPDC1B correlates with a poor prognosis in cancer patients (2,3). Studies have shown that DEPDC1B levels are upregulated in non-small cell lung cancer (NSCLC) and have an inverse correlation with patient survival. Ectopic expression of DEPDC1B in NSCLC activated Wnt/B-catenin signaling and enhanced cell migration and invasion while silencing DEPDC1B expression suppressed these traits (2).
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分子量
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Predicted: 58 kDa
Observed: 57 kDa -
基因ID
- 55789
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NCBI登录号
- NP_060839
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UniProt
- Q8WUY9
抗原
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