DEPDC1B 抗体 (C-Term)
DEPDC1B
适用: 人
WB, ELISA, IHC (p)
宿主: 兔
Polyclonal
unconjugated
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- 抗原 See all DEPDC1B products
- DEPDC1B (DEP Domain Containing 1B (DEPDC1B))
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抗原表位
- C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This DEPDC1B antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 特异性
- DEPDC1B antibody is human specific. At least two isoforms are known to exist, this antibody will only detect the largest isoform. DEPDC1B antibody is predicted to not cross-react with DEPDC1A.
- 纯化方法
- DEPDC1B antibody is affinity chromatography purified via peptide column.
- 免疫原
- DEPDC1B antibody was raised against a 19 amino acid peptide near the carboxy terminus of human DEPDC1B. The immunogen is located within the last 50 amino acids of DEPDC1B.
- 亚型
- IgG
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anti-DEP Domain Containing 1B (DEPDC1B) (AA 343-529) antibody
DEPDC1B 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-DEP Domain Containing 1B (DEPDC1B) (AA 430-529) antibodyDEPDC1B 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2H2 unconjugated
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- 应用备注
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DEPDC1B antibody can be used for detection of DEPDC1B by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL.
Antibody validated: Western Blot in human samples and Immunohistochemistry in human samples. All other applications and species not yet tested. - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- DEPDC1B antibody is supplied in PBS containing 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,4 °C
- 储存方法
- DEPDC1B antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- 抗原
- DEPDC1B (DEP Domain Containing 1B (DEPDC1B))
- 别名
- DEPDC1B (DEPDC1B 产品)
- 背景
- The DEP domain-containing 1B (DEPDC1B) protein was initially identified as a radiation response biomarker in human lymphoblastoid cell lines (1). Like the related protein DEPDC1A, expression of DEPDC1B correlates with a poor prognosis in cancer patients (2,3). Studies have shown that DEPDC1B levels are upregulated in non-small cell lung cancer (NSCLC) and have an inverse correlation with patient survival. Ectopic expression of DEPDC1B in NSCLC activated Wnt/B-catenin signaling and enhanced cell migration and invasion while silencing DEPDC1B expression suppressed these traits (2).
- 分子量
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Predicted: 58 kDa
Observed: 57 kDa - 基因ID
- 55789
- NCBI登录号
- NP_060839
- UniProt
- Q8WUY9
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