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Hexokinase 1 抗体 (C-Term)

This anti-Hexokinase 1 antibody is a 兔 多克隆 antibody detecting Hexokinase 1 in WB, ELISA, IF 和 IHC (p). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6992150
发货至: 中国

Quick Overview for Hexokinase 1 抗体 (C-Term) (ABIN6992150)

抗原

See all Hexokinase 1 (HK1) 抗体
Hexokinase 1 (HK1)

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This Hexokinase 1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    AA 830-880, C-Term

    特异性

    Hexokinase 1 antibody is human, mouse and rat reactive. Multiple isoforms of Hexokinase 1 are known to exist.

    纯化方法

    Hexokinase 1 antibody is affinity chromatography purified via peptide column.

    免疫原

    Hexokinase 1 antibody was raised against a 16 amino acid peptide near the carboxy terminus of human Hexokinase 1. The immunogen is located within amino acids 830 - 880 of Hexokinase 1.

    亚型

    IgG
  • 应用备注

    Hexokinase 1 antibody can be used for detection of Hexokinase 1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in rat samples, Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Hexokinase 1 antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,4 °C

    储存方法

    Hexokinase 1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
  • 抗原

    Hexokinase 1 (HK1)

    别名

    Hexokinase 1

    背景

    There are four major glucose-phosphorylating isoenzymes, designated Hexokinase 1 I, II, III, and IV (1). Hexokinase 1 activity is involved in the first step in several metabolic pathways including phosphorylation of glucose to produce glucose-6-phosphate, thus committing glucose to the glycolytic pathway (1,2). Hexokinase 1 2 is the predominant Hexokinase 1 isozyme expressed in insulin-responsive tissues such as skeletal muscle and its expression is insulin-responsive (3). It is involved in the increased rate of glycolysis seen in rapidly growing cancer cells (4).

    分子量

    Predicted: 101 kDa

    Observed: 103 kDa

    基因ID

    3098

    NCBI登录号

    NP_000179

    UniProt

    P19367

    途径

    Carbohydrate Homeostasis, Warburg Effect
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