Hexokinase 1 抗体 (C-Term)
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北京 101111
Quick Overview for Hexokinase 1 抗体 (C-Term) (ABIN6992150)
抗原
See all Hexokinase 1 (HK1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 830-880, C-Term
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特异性
- Hexokinase 1 antibody is human, mouse and rat reactive. Multiple isoforms of Hexokinase 1 are known to exist.
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纯化方法
- Hexokinase 1 antibody is affinity chromatography purified via peptide column.
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免疫原
- Hexokinase 1 antibody was raised against a 16 amino acid peptide near the carboxy terminus of human Hexokinase 1. The immunogen is located within amino acids 830 - 880 of Hexokinase 1.
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亚型
- IgG
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应用备注
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Hexokinase 1 antibody can be used for detection of Hexokinase 1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in rat samples, Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Hexokinase 1 antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- Hexokinase 1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- Hexokinase 1 (HK1)
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别名
- Hexokinase 1
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背景
- There are four major glucose-phosphorylating isoenzymes, designated Hexokinase 1 I, II, III, and IV (1). Hexokinase 1 activity is involved in the first step in several metabolic pathways including phosphorylation of glucose to produce glucose-6-phosphate, thus committing glucose to the glycolytic pathway (1,2). Hexokinase 1 2 is the predominant Hexokinase 1 isozyme expressed in insulin-responsive tissues such as skeletal muscle and its expression is insulin-responsive (3). It is involved in the increased rate of glycolysis seen in rapidly growing cancer cells (4).
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分子量
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Predicted: 101 kDa
Observed: 103 kDa -
基因ID
- 3098
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NCBI登录号
- NP_000179
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UniProt
- P19367
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途径
- Carbohydrate Homeostasis, Warburg Effect
抗原
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