MEK1/2 抗体 (AA 240-290)
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Quick Overview for MEK1/2 抗体 (AA 240-290) (ABIN6992146)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 240-290
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特异性
- MEK1/2 antibody is human, mouse, and rat reactive. This antibody detects both MEK1 and MEK2.
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纯化方法
- MEK1/2 antibody is affinity chromatography purified via peptide column.
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免疫原
- MEK1/2 antibody was raised against a 15 amino acid peptide near the center of human MEK1. The immunogen is located within amino acids 240 - 290 of MEK1/2.
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亚型
- IgG
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应用备注
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MEK1/2 antibody can be used for detection of MEK1/2 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- MEK1/2 antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- MEK1/2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- MEK1/2 (MAP2K1/2) (Mitogen-Activated Protein Kinase Kinase 1/2 (MAP2K1/2))
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别名
- MEK1/2
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背景
- The mitogen-activated protein kinase kinase 1 (MAP2K1, also known as MEK1) and the highly homologous MEK2 are members of the dual specificity protein kinase family (1). MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals (2). MEK1 lies upstream of MAP kinases and stimulates the enzymatic activity of MAP kinases upon wide variety of extra- and intracellular signals. As an essential component of MAP kinase signal transduction pathway, MEK1 is involved in many cellular processes such as proliferation, differentiation, transcription regulation and development (2).
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分子量
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Predicted: 43 kDa
Observed: 44 kDa -
基因ID
- 5604
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NCBI登录号
- NP_002746
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UniProt
- Q0VD16
抗原
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