Deltex Homolog 4 抗体 (AA 230-280)
This anti-Deltex Homolog 4 antibody is a 兔 多克隆 antibody detecting Deltex Homolog 4 in ELISA, WB, IF 和 IHC (p). Suitable for 人 和 小鼠.
Quick Overview for Deltex Homolog 4 抗体 (AA 230-280) (ABIN6992091)
抗原
See all Deltex Homolog 4 (DTX4) 抗体
Deltex Homolog 4 (DTX4)
(Deltex Homolog 4 (Drosophila) (DTX4))
适用
人, 小鼠
宿主
兔
克隆类型
多克隆
标记
This Deltex Homolog 4 antibody is un-conjugated
应用范围
ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
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抗原表位
- AA 230-280
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特异性
- DTX4 antibody is human and mouse reactive. At least two isoforms of DTX4 are known to exist, this antibody will detect both isoforms. DTX4 antibody is predicted to not cross-react with other DTX protein family members.
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纯化方法
- DTX4 antibody is affinity chromatography purified via peptide column.
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免疫原
- DTX4 antibody was raised against a 19 amino acid peptide near the center of human DTX4. The immunogen is located within amino acids 230 - 280 of DTX4.
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亚型
- IgG
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anti-Deltex Homolog 4 (Drosophila) (DTX4) (AA 56-83), (N-Term) antibody
DTX4 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB23716 unconjugated
anti-Deltex Homolog 4 (Drosophila) (DTX4) (AA 167-432) antibodyDTX4 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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DTX4 antibody can be used for detection of DTX4 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- DTX4 antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- DTX4 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- Deltex Homolog 4 (DTX4) (Deltex Homolog 4 (Drosophila) (DTX4))
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别名
- DTX4
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背景
- The Deltex 4 E3 ubiquitin ligase (DTX4) is a member of a protein family that is involved in Notch signaling and neurogenesis (1). Recent studies have shown that DTX4 is also associated with the innate immune response (2). Following the activation of type I interferon signaling, the Nod-like receptor protein 4 (NLRP4) recruits DTX4 for Lys48-linked polyubiquitination and degradation of the kinase TBK1 (NAK), thereby maintaining immune homeostasis during antiviral innate immunity (2).
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分子量
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Predicted: 68 kDa
Observed: 68 kDa -
基因ID
- 23220
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NCBI登录号
- NP_055992
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UniProt
- Q9Y2E6
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途径
- Notch Signaling
抗原
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