HES5 抗体 (N-Term)
Quick Overview for HES5 抗体 (N-Term) (ABIN6992090)
抗原
See all HES5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- HES5 antibody is human, mouse and rat reactive. At least two isoforms of HES5 are known to exist, this antibody will detect both isoforms.
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纯化方法
- HES5 antibody is affinity chromatography purified via peptide column.
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免疫原
- HES5 antibody was raised against a 19 amino acid peptide near the amino terminus of human HES5. The immunogen is located within the first 50 amino acids of HES5.
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亚型
- IgG
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anti-Hairy and Enhancer of Split 5 (HES5) antibody
HES5 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Hairy and Enhancer of Split 5 (HES5) (AA 21-120) antibodyHES5 适用: 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Hairy and Enhancer of Split 5 (HES5) (AA 1-50) antibodyHES5 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Hairy and Enhancer of Split 5 (HES5) (AA 83-95) antibodyHES5 适用: 人, 小鼠, 大鼠, 犬, Cow, 猴 WB, ELISA, IHC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Hairy and Enhancer of Split 5 (HES5) (AA 1-166) antibodyHES5 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Hairy and Enhancer of Split 5 (HES5) (AA 81-115) antibodyHES5 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB51477 unconjugated
anti-Hairy and Enhancer of Split 5 (HES5) (AA 28-121) antibodyHES5 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3B6 unconjugated
anti-Hairy and Enhancer of Split 5 (HES5) (AA 28-121) antibodyHES5 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3C5 unconjugated
anti-Hairy and Enhancer of Split 5 (HES5) (C-Term) antibodyHES5 适用: 人, 小鼠, 犬, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Hairy and Enhancer of Split 5 (HES5) antibodyHES5 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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HES5 antibody can be used for detection of HES5 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in human and mouse samples and Immunofluorescence in human and mouse samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- HES5 antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- HES5 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- HES5 (Hairy and Enhancer of Split 5 (HES5))
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别名
- HES5
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背景
- HES5 is a member of the HES family of transcriptional repressors, which are the mammalian homologs of the Drosophila Hairy and Enhancer of Split and contain basic Helix-loop-helix (bHLH) and Orange domains (1). The HES5 gene is a downstream target of the Notch signaling pathway and its expression is downregulated during human cartilage differentiation (2). HES5 can directly repress transcription of the E3 ligase FBW7-beta, creating a feedback loop that modulates Notch-mediated intestinal and neural stem cell fate decisions (3).
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分子量
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Predicted: 18 kDa
Observed: 17 kDa -
基因ID
- 388585
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NCBI登录号
- NP_001010926
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UniProt
- Q5TA89
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途径
- Stem Cell Maintenance, Tube Formation
抗原
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