LIMA1 抗体 (N-Term)
-
- 抗原 See all LIMA1 抗体
- LIMA1 (LIM Domain and Actin Binding 1 (LIMA1))
-
抗原表位
- AA 230-280, N-Term
-
适用
- 人
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This LIMA1 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 特异性
- LIMA1 antibody is human specific. At least four isoforms of LIMA1 are known to exist, this antibody will only detect the three largest isoforms.
- 纯化方法
- LIMA1 antibody is affinity chromatography purified via peptide column.
- 免疫原
- LIMA1 antibody was raised against an 18 amino acid peptide near the amino terminus of human LIMA1. The immunogen is located within amino acids 230 - 280 of LIMA1.
- 亚型
- IgG
- Top Product
- Discover our top product LIMA1 Primary Antibody
-
anti-LIM Domain and Actin Binding 1 (LIMA1) (AA 1-598) antibody
LIMA1 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1B7 unconjugated
anti-LIM Domain and Actin Binding 1 (LIMA1) (N-Term) antibodyLIMA1 适用: 人, 小鼠, 大鼠, 兔, 马 WB 宿主: 兔 Polyclonal unconjugated
anti-LIM Domain and Actin Binding 1 (LIMA1) antibodyLIMA1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-LIM Domain and Actin Binding 1 (LIMA1) (AA 502-551) antibodyLIMA1 适用: 人, 小鼠, 兔, Cow, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-LIM Domain and Actin Binding 1 (LIMA1) (AA 143-192) antibodyLIMA1 适用: 人, 小鼠, 兔, 马 WB 宿主: 兔 Polyclonal unconjugated
anti-LIM Domain and Actin Binding 1 (LIMA1) (C-Term) antibodyLIMA1 适用: 人, 小鼠, 大鼠, 兔, 马, Cow WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-LIM Domain and Actin Binding 1 (LIMA1) (C-Term) antibodyLIMA1 适用: 人, 小鼠, 大鼠, 兔, 马, Cow, 斑马鱼, 猴, Hamster WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-LIM Domain and Actin Binding 1 (LIMA1) (AA 560-759) antibodyLIMA1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-LIM Domain and Actin Binding 1 (LIMA1) (Middle Region) antibodyLIMA1 适用: 人, 小鼠, 大鼠, 兔, 马, Cow, 犬, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
-
LIMA1 antibody can be used for detection of LIMA1 by Western blot at 0.5 - 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. - 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- LIMA1 antibody is supplied in PBS containing 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,4 °C
- 储存方法
- LIMA1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
-
- 抗原
- LIMA1 (LIM Domain and Actin Binding 1 (LIMA1))
- 别名
- LIMA1 (LIMA1 产品)
- 别名
- eplin antibody, LIMA1 antibody, EPLIN antibody, MGC146397 antibody, SREBP3 antibody, 1110021C24Rik antibody, 3526402A12Rik antibody, D15Ertd366e antibody, Eplin antibody, LIM domain and actin binding 1 antibody, Lima1 antibody, LIMA1 antibody, lima1 antibody
- 背景
- The Lim domain and actin-binding protein 1 (LIMA1) is cytoskeleton-associated protein that inhibits actin filament depolymerization and cross-links filaments in bundles and is downregulated in some cancer cell lines (1,2). LIMA1 is also a key molecule linking the cadherin-catenin complex to the actin cytoskeleton (3). Recent studies have shown that EGF activates ERK1/2-dependent phosphorylation, ubiquitination and degradation of LIMA1, leading to increased invasiveness and metastasis of metastatic prostate cancer models (4).
- 分子量
-
Predicted: 50, 66, 84 kDa
Observed: 65 kDa - 基因ID
- 51474
- NCBI登录号
- NP_001107018
- UniProt
- Q9UHB6
-
