GJB2 抗体 (AA 80-130)
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北京 101111
Quick Overview for GJB2 抗体 (AA 80-130) (ABIN6992084)
抗原
See all GJB2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 80-130
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特异性
- GJB2 antibody is human specific.
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纯化方法
- GJB2 antibody is affinity chromatography purified via peptide column.
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免疫原
- GJB2 antibody was raised against a 16 amino acid peptide near the center of human GJB2. The immunogen is located within amino acids 80 - 130 of GJB2.
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亚型
- IgG
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应用备注
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GJB2 antibody can be used for detection of GJB2 by Western blot at 1 - 2 μ,g/mL.
Antibody validated: Western Blot in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- GJB2 antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- GJB2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- GJB2 (Gap Junction Protein, beta 2, 26kDa (GJB2))
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别名
- GJB2
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背景
- The Gap junction beta-2 protein (GJB2), also known as Connexin 26, is member of the gap junction protein family which form structures that were shown to consist of cell-to-cell channels that facilitate the transfer of ions and small molecules between cells (1). Mutations in the GJB2 gene are thought to be responsible for as much as 35-45 % of congenital sensorineural hearing loss in some populations (2). Other mutations in this gene have also been linked to a wide array of skin diseases (3).
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分子量
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Predicted: 25 kDa
Observed: 26 kDa -
基因ID
- 2706
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NCBI登录号
- NP_003995
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UniProt
- P29033
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途径
- Sensory Perception of Sound, Cell-Cell Junction Organization
抗原
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