RHOG 抗体 (N-Term)
Quick Overview for RHOG 抗体 (N-Term) (ABIN6992068)
抗原
See all RHOG 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 40-90, N-Term
-
特异性
- RHOG antibody is human, mouse and rat reactive.
-
纯化方法
- RHOG antibody is affinity chromatography purified via peptide column.
-
免疫原
- RHOG antibody was raised against a 15 amino acid peptide near the amino terminus of human RHOG. The immunogen is located within amino acids 40 - 90 of RHOG.
-
亚型
- IgG
-
-
-
-
应用备注
-
RHOG antibody can be used for detection of RHOG by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL.
Antibody validated: Western Blot in human samples and Immunohistochemistry in mouse samples. All other applications and species not yet tested. -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- RHOG antibody is supplied in PBS containing 0.02 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C,4 °C
-
储存方法
- RHOG antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
-
-
- RHOG (Ras Homolog Family Member G (RHOG))
-
别名
- RHOG
-
背景
- The ras homolog family member G (RHOG), also known as rho-related GTP-binding protein, is a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades (1). RHOG controls a pathway that requires the microtubule network and activates Rac1 and Cdc42Hs independently of their growth factor signaling pathway (2). RHOG is also involved in the transcriptional regulation of interferon-gamma and nuclear factor of activated T cells (NFAT) and the regulation of the actin skeleton in lymphocytes (3).
-
分子量
-
Predicted: 21 kDa
Observed: 23 kDa -
基因ID
- 391
-
NCBI登录号
- NP_001656
-
UniProt
- P84095
-
途径
- RTK signaling
抗原
-