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LC3B 抗体 (AA 20-70)

This anti-LC3B antibody is a 兔 多克隆 antibody detecting LC3B in WB, ELISA 和 IHC (p). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6992057
发货至: 中国

Quick Overview for LC3B 抗体 (AA 20-70) (ABIN6992057)

抗原

See all LC3B (MAP1LC3B) 抗体
LC3B (MAP1LC3B) (Microtubule-Associated Protein 1 Light Chain 3 beta (MAP1LC3B))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This LC3B antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    AA 20-70

    特异性

    MAP1LC3 antibody is human, mouse and rat reactive. Multiple isoforms MAP1LC3 are known to exist. MAP1LC3 antibody is predicted to detect MAP1LC3A, MAP1LC3B, and MAP1LC3C.

    纯化方法

    MAP1LC3 antibody is affinity chromatography purified via peptide column.

    免疫原

    MAP1LC3 antibody was raised against a 12 amino acid peptide near the center of human MAP1LC3A. The immunogen is located within amino acids 20 - 70 of MAP1LC3.

    亚型

    IgG
  • 应用备注

    MAP1LC3 antibody can be used for detection of MAP1LC3 by Western blot at 0.5 - 1 μ,g/mL. Antibody can also be used for Immunohistochemistry starting at 5 μ,g/mL.

    Antibody validated: Western Blot in human samples and Immunohistochemistry in rat samples. All other applications and species not yet tested.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    MAP1LC3 antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,4 °C

    储存方法

    MAP1LC3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
  • 抗原

    LC3B (MAP1LC3B) (Microtubule-Associated Protein 1 Light Chain 3 beta (MAP1LC3B))

    别名

    MAP1LC3

    背景

    Microtubule-associated proteins (MAPs) regulate microtubule stability and play critical roles in neuronal development and plasticity (1). MAP1LC3 is a subfamily of three related proteins belonging to the MAP1 LC3 family and it includes MAP1LC3A, MAP1LC3B, and MAP1LC3C (2). MAP1LC3 is the mammalian homolog of yeast ATG8 and is essential for autophagy and associated with the autophagosome membranes after processing (3). The three isoforms exhibit distinct expression patterns and both MAP1LC3A and MAP1LC3B but not MAP1LC3B, are post-translationally modified, suggesting the three isoforms may have different physiological functions (4).

    分子量

    Predicted: 13 kDa

    Observed: 18 kDa

    基因ID

    84557

    NCBI登录号

    NP_115903

    UniProt

    Q9H492

    途径

    Autophagy
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