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UVRAG 抗体 (C-Term)

Name: UVRAG 抗体 (C-Term)
Brand: antibodies-online
SKU: ABIN6992055
Availability: OutOfStock

UVRAG 适用: 人, 小鼠 WB, ELISA, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated

产品编号 ABIN6992055

发货至: 中国

Datasheet as PDF

抗原 See all UVRAG 抗体

UVRAG (UV Radiation Resistance Associated Gene (UVRAG))
抗原表位
9

8

6

3

2

2

2

1

1

1

1

1

1

1

1

1

1

1
AA 490-540, C-Term
适用
57

37

30

1

1

1

1

1

1

1

1
人, 小鼠
宿主
53

4
兔
Compatible Secondaries
克隆类型
55

2
多克隆
标记
25

5

3

3

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1
This UVRAG antibody is un-conjugated
应用范围
50

15

13

11

11

9

9

6

5

2

1
Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

特异性

UVRAG antibody is human and mouse reactive.

纯化方法

UVRAG antibody is affinity chromatography purified via peptide column.

免疫原

UVRAG antibody was raised against an 18 amino acid peptide near the carboxy terminus of human UVRAG. The immunogen is located within amino acids 490 - 540 of UVRAG.

亚型

IgG

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anti-UV Radiation Resistance Associated Gene (UVRAG) (AA 501-699) antibody
UVRAG 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

anti-UV Radiation Resistance Associated Gene (UVRAG) (AA 375-425) antibody
UVRAG 适用: 人 WB, ELISA, IF, IHC 宿主: 兔 Polyclonal unconjugated

anti-UV Radiation Resistance Associated Gene (UVRAG) (AA 601-699) antibody
UVRAG 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2E8 unconjugated

anti-UV Radiation Resistance Associated Gene (UVRAG) antibody
UVRAG 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated

anti-UV Radiation Resistance Associated Gene (UVRAG) (C-Term) antibody (FITC)
UVRAG 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal FITC

anti-UV Radiation Resistance Associated Gene (UVRAG) (C-Term) antibody (PE)
UVRAG 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal PE

anti-UV Radiation Resistance Associated Gene (UVRAG) (C-Term) antibody (PerCP)
UVRAG 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal PerCP

anti-UV Radiation Resistance Associated Gene (UVRAG) (C-Term) antibody (Atto 488)
UVRAG 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal Atto 488

anti-UV Radiation Resistance Associated Gene (UVRAG) (C-Term) antibody (Atto 594)
UVRAG 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal Atto 594

anti-UV Radiation Resistance Associated Gene (UVRAG) (AA 666-699), (C-Term) antibody
UVRAG 适用: 人, 小鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB10849 unconjugated

应用备注

UVRAG antibody can be used for detection of UVRAG by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in mouse samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

限制

仅限研究用
状态

Liquid

浓度

1 mg/mL

缓冲液

UVRAG antibody is supplied in PBS containing 0.02 % sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C,4 °C

储存方法

UVRAG antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
抗原

UVRAG (UV Radiation Resistance Associated Gene (UVRAG))

别名

UVRAG (UVRAG 产品)

别名

DHTX antibody, VPS38 antibody, p63 antibody, 9530039D02Rik antibody, AI648770 antibody, BB124205 antibody, Uvrag1 antibody, Uvragl antibody, zgc:56164 antibody, uvrag antibody, MGC81810 antibody, UVRAG antibody, MGC131135 antibody, CG6116 antibody, Dmel\\CG6116 antibody, UV radiation resistance associated antibody, UV radiation resistance associated gene antibody, UV radiation resistance associated S homeolog antibody, UV radiation resistance associated L homeolog antibody, UV-resistance associated gene antibody, UVRAG antibody, Uvrag antibody, uvrag antibody, uvrag.S antibody, uvrag.L antibody

背景

The class III type phosphoinositide 3-kinase (PI3KC3) / Vps34 regulates vacuolar trafficking as well as autophagy (1). UVRAG (UV radiation resistance-associated gene) is associated with the Beclin-1/PI3KC3 complex and promotes PI3KC3 enzymatic activity and autophagy, while suppressing proliferation (2). UVRAG is highly expressed in brain, lung, kidney and liver and contains one C2 domain, which is involved in calcium-dependent phospholipid binding. Beclin-1 binding to UVRAG promotes both autophagosome maturation and endocytic trafficking (3). UVRAG is also a potential tumor suppressor protein with frameshift mutations observed in colon and gastric carcinomas (4,5).

分子量

Predicted: 77 kDa

Observed: 75 kDa

基因ID

7405

NCBI登录号

NP_003360

UniProt

Q9P2Y5