UVRAG 抗体 (C-Term)
Quick Overview for UVRAG 抗体 (C-Term) (ABIN6992055)
抗原
See all UVRAG 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 490-540, C-Term
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特异性
- UVRAG antibody is human and mouse reactive.
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纯化方法
- UVRAG antibody is affinity chromatography purified via peptide column.
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免疫原
- UVRAG antibody was raised against an 18 amino acid peptide near the carboxy terminus of human UVRAG. The immunogen is located within amino acids 490 - 540 of UVRAG.
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亚型
- IgG
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anti-UV Radiation Resistance Associated Gene (UVRAG) (AA 501-699) antibody
UVRAG 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-UV Radiation Resistance Associated Gene (UVRAG) (AA 375-425) antibodyUVRAG 适用: 人 WB, ELISA, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-UV Radiation Resistance Associated Gene (UVRAG) (AA 601-699) antibodyUVRAG 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2E8 unconjugated
anti-UV Radiation Resistance Associated Gene (UVRAG) antibodyUVRAG 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-UV Radiation Resistance Associated Gene (UVRAG) antibody (HRP)UVRAG 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal HRP
anti-UV Radiation Resistance Associated Gene (UVRAG) antibody (FITC)UVRAG 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal FITC
anti-UV Radiation Resistance Associated Gene (UVRAG) antibody (Biotin)UVRAG 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal Biotin
anti-UV Radiation Resistance Associated Gene (UVRAG) antibody (PE)UVRAG 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal PE
anti-UV Radiation Resistance Associated Gene (UVRAG) antibody (PerCP)UVRAG 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal PerCP
anti-UV Radiation Resistance Associated Gene (UVRAG) antibody (APC)UVRAG 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal APC
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应用备注
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UVRAG antibody can be used for detection of UVRAG by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in mouse samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- UVRAG antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- UVRAG antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- UVRAG (UV Radiation Resistance Associated Gene (UVRAG))
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别名
- UVRAG
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背景
- The class III type phosphoinositide 3-kinase (PI3KC3) / Vps34 regulates vacuolar trafficking as well as autophagy (1). UVRAG (UV radiation resistance-associated gene) is associated with the Beclin-1/PI3KC3 complex and promotes PI3KC3 enzymatic activity and autophagy, while suppressing proliferation (2). UVRAG is highly expressed in brain, lung, kidney and liver and contains one C2 domain, which is involved in calcium-dependent phospholipid binding. Beclin-1 binding to UVRAG promotes both autophagosome maturation and endocytic trafficking (3). UVRAG is also a potential tumor suppressor protein with frameshift mutations observed in colon and gastric carcinomas (4,5).
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分子量
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Predicted: 77 kDa
Observed: 75 kDa -
基因ID
- 7405
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NCBI登录号
- NP_003360
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UniProt
- Q9P2Y5
抗原
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