Rubicon 抗体 (N-Term)
Quick Overview for Rubicon 抗体 (N-Term) (ABIN6992053)
抗原
See all Rubicon (KIAA0226) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 240-290, N-Term
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特异性
- Rubicon antibody is human, mouse and rat reactive. Multiple isoforms of Rubicon are known to exist.
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纯化方法
- Rubicon antibody is affinity chromatography purified via peptide column.
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免疫原
- Rubicon antibody was raised against a 16 amino acid peptide near the amino terminus of human Rubicon. The immunogen is located within amino acids 240 - 290 of Rubicon.
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亚型
- IgG
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anti-KIAA0226 (KIAA0226) (AA 656-684) antibody
KIAA0226 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB18182 unconjugated
anti-KIAA0226 (KIAA0226) (AA 1-375) antibodyKIAA0226 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2G8 unconjugated
anti-KIAA0226 (KIAA0226) (AA 859-972) antibodyKIAA0226 适用: 人 ELISA 宿主: 小鼠 Monoclonal 4F5B5 unconjugated
anti-KIAA0226 (KIAA0226) (N-Term) antibodyKIAA0226 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-KIAA0226 (KIAA0226) (N-Term) antibody (HRP)KIAA0226 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal HRP
anti-KIAA0226 (KIAA0226) (N-Term) antibody (FITC)KIAA0226 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal FITC
anti-KIAA0226 (KIAA0226) (N-Term) antibody (Biotin)KIAA0226 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal Biotin
anti-KIAA0226 (KIAA0226) (N-Term) antibody (PE)KIAA0226 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal PE
anti-KIAA0226 (KIAA0226) (N-Term) antibody (PerCP)KIAA0226 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal PerCP
anti-KIAA0226 (KIAA0226) (N-Term) antibody (APC)KIAA0226 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal APC
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应用备注
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Rubicon body can be used for detection of Rubicon by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rubicon antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- Rubicon antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- Rubicon (KIAA0226) (KIAA0226)
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别名
- Rubicon
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背景
- Two Beclin-1-interacting proteins, the run domain Beclin-1 interacting and cysteine-rich containing protein (Rubicon) and ATG14L, reciprocally regulate autophagy at different stages. Knockdown of Rubicon caused enhancement of autophagy while that of ATG14L caused a defect in autophagosome formation (1). Rubicon functions as part of a Beclin-1-PIK3C3-containing autophagy complex and is also an essential, positive regulator of the NAPDH oxidase complex (2). Upon microbial infection or TLR2 activation, Rubicon interacts with the CYBA subunit of the NAPDH oxidase complex, leading to a burst of reactive oxygen species and inflammatory cytokines (2).
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分子量
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Predicted: 90, 101, 109 kDa
Observed: 91, 99 kDa -
基因ID
- 9711
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NCBI登录号
- XP_005269431
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UniProt
- Q92622
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途径
- Autophagy
抗原
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