SHBG 抗体 (AA 220-270)
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北京 101111
Quick Overview for SHBG 抗体 (AA 220-270) (ABIN6992049)
抗原
See all SHBG 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 220-270
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特异性
- SHBG antibody is human, mouse, and rat reactive. At least three isoforms of SHBG are known to exist, this antibody will detect all three isoforms.
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纯化方法
- SHBG antibody is affinity chromatography purified via peptide column.
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免疫原
- SHBG antibody was raised against a 16 amino acid peptide near the center of human SHBG. The immunogen is located within amino acids 220 - 270 of SHBG.
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亚型
- IgG
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应用备注
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SHBG antibody can be used for detection of SHBG by Western blot at 1 - 2 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples and Immunofluorescence in mouse samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- SHBG antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- SHBG antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- SHBG (Sex Hormone Binding Globulin (SHBG))
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别名
- SHBG
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背景
- SHBG is a steroid binding protein that was first described as a plasma protein secreted by the liver and is thought to participate in the regulation of steroid responses. SHBG transports androgens and estrogens in the blood, binding each steroid molecule as a dimer formed from identical or nearly identical monomers (1). Low plasma SHBG levels are associated with obesity, abdominal adiposity, metabolic syndrome, and predict the development of type 2 diabetes (2,3). Polymorphisms in this gene have been associated with polycystic ovary syndrome and type 2 diabetes mellitus (4).
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分子量
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Predicted: 25, 26, 31, 32, 38, 44 kDa
Observed: 35 kDa -
基因ID
- 6462
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NCBI登录号
- NP_001031
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UniProt
- P04278
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途径
- Hormone Transport
抗原
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