HDAC6 抗体 (C-Term)
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Quick Overview for HDAC6 抗体 (C-Term) (ABIN6992036)
抗原
See all HDAC6 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- HDAC6 antibody is human and mouse reactive. Multiple isoforms of HDAC6 are known to exist. HDAC6 antibody is predicted to not cross-react with other members of the HDAC family.
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纯化方法
- HDAC6 antibody is affinity chromatography purified via peptide column.
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免疫原
- HDAC6 antibody was raised against a 16 amino acid peptide near the carboxy terminus of human HDAC6. The immunogen is located within the last 50 amino acids of HDAC6.
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亚型
- IgG
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应用备注
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HDAC6 body can be used for detection of HDAC6 by Western blot at 0.5 - 1 μ,g/mL. Antibody can also be used for Immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- HDAC6 antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- HDAC6 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- HDAC6 (Histone Deacetylase 6 (HDAC6))
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别名
- HDAC6
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背景
- The histone deacetylase (HDAC) family contains multiple members which are divided into four classes. Class II of the HDAC family comprises six members, HDAC4, 5, 6, 7, 9 and 10, each of which appear to have tissue-specific roles (1). HDAC6 contains an internal duplication of two catalytic domains which appear to function independently of each other (2). HDAC6 has been shown to be part of the microtubule network and acts as a specific alpha-tubulin deacetylase, and has been suggested to be a potential therapeutic target in neurodegenerative disease (3).
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分子量
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Predicted: 55 kDa
Observed: 32 kDa -
基因ID
- 10013
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NCBI登录号
- NP_006035
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UniProt
- Q9UBN7
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途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling
抗原
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