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HDAC6 抗体 (C-Term)

This anti-HDAC6 antibody is a 兔 多克隆 antibody detecting HDAC6 in WB, ELISA, IF 和 IHC (p). Suitable for 人 和 小鼠.
产品编号 ABIN6992036
发货至: 中国

Quick Overview for HDAC6 抗体 (C-Term) (ABIN6992036)

抗原

See all HDAC6 抗体
HDAC6 (Histone Deacetylase 6 (HDAC6))

适用

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人, 小鼠

宿主

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克隆类型

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多克隆

标记

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This HDAC6 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    C-Term

    特异性

    HDAC6 antibody is human and mouse reactive. Multiple isoforms of HDAC6 are known to exist. HDAC6 antibody is predicted to not cross-react with other members of the HDAC family.

    纯化方法

    HDAC6 antibody is affinity chromatography purified via peptide column.

    免疫原

    HDAC6 antibody was raised against a 16 amino acid peptide near the carboxy terminus of human HDAC6. The immunogen is located within the last 50 amino acids of HDAC6.

    亚型

    IgG
  • 应用备注

    HDAC6 body can be used for detection of HDAC6 by Western blot at 0.5 - 1 μ,g/mL. Antibody can also be used for Immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    HDAC6 antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,4 °C

    储存方法

    HDAC6 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
  • 抗原

    HDAC6 (Histone Deacetylase 6 (HDAC6))

    别名

    HDAC6

    背景

    The histone deacetylase (HDAC) family contains multiple members which are divided into four classes. Class II of the HDAC family comprises six members, HDAC4, 5, 6, 7, 9 and 10, each of which appear to have tissue-specific roles (1). HDAC6 contains an internal duplication of two catalytic domains which appear to function independently of each other (2). HDAC6 has been shown to be part of the microtubule network and acts as a specific alpha-tubulin deacetylase, and has been suggested to be a potential therapeutic target in neurodegenerative disease (3).

    分子量

    Predicted: 55 kDa

    Observed: 32 kDa

    基因ID

    10013

    NCBI登录号

    NP_006035

    UniProt

    Q9UBN7

    途径

    Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling
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