HDAC1 抗体 (C-Term)
Quick Overview for HDAC1 抗体 (C-Term) (ABIN6992034)
抗原
See all HDAC1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- HDAC1 antibody is human, mouse and rat reactive. HDAC1 antibody is predicted to not cross-react with other members of the HDAC family.
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纯化方法
- HDAC1 antibody is affinity chromatography purified via peptide column.
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免疫原
- HDAC1 antibody was raised against a 19 amino acid peptide near the carboxy terminus of human HDAC1. The immunogen is located within the last 50 amino acids of HDAC1.
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亚型
- IgG
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应用备注
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HDAC1 antibody can be used for detection of HDAC1 by Western blot at 1 - 2 μ,g/mL.
Antibody validated: Western Blot in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- HDAC1 antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- HDAC1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- HDAC1 (Histone Deacetylase 1 (HDAC1))
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别名
- HDAC1
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背景
- The histone deacetylase (HDAC) family contains multiple members which are divided into four classes. Class I of the HDAC family comprises four members, HDAC1, 2, 3, and 8, each of which contains a deacetylase domain and exhibits a different, individual substrate specificity and function in vivo (1). HDAC1 is responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4) (1,2). HDAC1 gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events (3,4).
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分子量
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Predicted: 53 kDa
Observed: 54 kDa -
基因ID
- 3065
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NCBI登录号
- NP_004955
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UniProt
- Q13547
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途径
- Neurotrophin Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Mitotic G1-G1/S Phases, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Negative Regulation of intrinsic apoptotic Signaling, Embryonic Body Morphogenesis
抗原
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