GABARAPL2 抗体 (C-Term)
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Quick Overview for GABARAPL2 抗体 (C-Term) (ABIN6992033)
抗原
See all GABARAPL2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- GABARAPL2 antibody is human, mouse and rat reactive. Multiple isoforms of GABARAPL2 are known to exist.
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纯化方法
- GABARAPL2 antibody is affinity chromatography purified via peptide column.
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免疫原
- GABARAPL2 antibody was raised against a 15 amino acid peptide near the carboxy terminus of human GABARAPL2. The immunogen is located within the last 50 amino acids of GABARAPL2.
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亚型
- IgG
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应用备注
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GABARAPL2 antibody can be used for detection of GABARAPL2 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry at 5 μ,g/mL. For Immunoflorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in mouse and rat samples and Immunofluorescence in mouse and rat samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- GABARAPL2 antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- GABARAPL2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- GABARAPL2 (GABA(A) Receptor-Associated Protein-Like 2 (GABARAPL2))
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别名
- GABARAPL2
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背景
- Gamma-aminobutyric acid (GABA) is the main inhibitory transmitter by increasing a Cl-conductance that inhibits neuronal firing in the central nervous system (1). It has been shown to activate both ionotropic (GABAA) and metabotropic (GABAB) receptors as well as a third class of receptors called GABAC (2). GABARAPL2 (GABAA receptor-associated protein-like 2), also known as GATE16, was initially identified as a membrane transport modulator and is a mammalian ortholog to the autophagy protein ATG8 (3,4). It is thought that GABARAPL2 and other members of the ATG8 family act as scaffolds for assembly of the Unc-51 like kinase (ULK) complex in the formation of autophagosomes (5).
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分子量
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Predicted: 13 kDa
Observed: 13 kDa -
基因ID
- 11345
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NCBI登录号
- NP_009216
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UniProt
- P60520
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途径
- Autophagy
抗原
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