MFN1 抗体 (N-Term)
Quick Overview for MFN1 抗体 (N-Term) (ABIN6992021)
抗原
See all MFN1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 20-70, N-Term
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特异性
- MFN1 antibody is human, mouse and rat reactive. MFN1 antibody is predicted to not cross-react with MFN2.
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纯化方法
- MFN1 antibody is affinity chromatography purified via peptide column.
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免疫原
- MFN1 antibody was raised against a 17 amino acid peptide near the amino terminus of human MFN1. The immunogen is located within amino acids 20 - 70 of MFN1.
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亚型
- IgG
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anti-Mitofusin 1 (MFN1) (AA 1-741) antibody
MFN1 适用: 人 WB, ELISA, RNAi 宿主: 小鼠 Monoclonal 3C9 unconjugated
anti-Mitofusin 1 (MFN1) (AA 1-234) antibodyMFN1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Mitofusin 1 (MFN1) (AA 651-741) antibodyMFN1 适用: 小鼠, 大鼠, 兔, 小鸡 WB, ELISA, FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Mitofusin 1 (MFN1) (AA 622-741) antibodyMFN1 适用: 人 WB, IHC, ELISA, IP 宿主: 兔 Polyclonal unconjugated
anti-Mitofusin 1 (MFN1) (AA 622-741) antibodyMFN1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Mitofusin 1 (MFN1) (AA 745-756) antibodyMFN1 适用: 人, 兔, 犬, 马, 猴 IHC, IHC (p) 宿主: 山羊 Polyclonal unconjugated
anti-Mitofusin 1 (MFN1) (Internal Region) antibodyMFN1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Mitofusin 1 (MFN1) (AA 209-469) antibodyMFN1 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 4D11 unconjugated
anti-Mitofusin 1 (MFN1) (AA 622-741) antibodyMFN1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Mitofusin 1 (MFN1) (AA 1-227) antibodyMFN1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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MFN1 antibody can be used for detection of MFN1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunocytochemistry at 5 μ,g/mL.
Antibody validated: Western Blot in human samples and Immunocytochemistry in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- MFN1 antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- MFN1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- MFN1 (Mitofusin 1 (MFN1))
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别名
- MFN1
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背景
- Mitofusin 1 (MFN1) and the related protein MFN2 are mitochondrial membrane GTPase proteins that play a central role in mitochondrial metabolism and may be associated with obesity and/or apoptosis processes (1,2). MFN1 and MFN2 form homotypic and heterotypic complexes and coordinately regulate mitochondrial fusion and are essential for embryonic development (3). When ectopically expressed, MFN1 inhibits the apoptosis-associated amino-terminal conformation change in the apoptotic protein Bax but not its mitochondrial translocation, indicating that MFN1 is involved in the regulating the activation of Bax on the outer mitochondrial membrane (4).
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分子量
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Predicted: 82 kDa
Observed: 83 kDa -
基因ID
- 55669
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NCBI登录号
- NP_284941
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UniProt
- Q8IWA4
抗原
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