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MFN1 抗体 (N-Term)

MFN1 适用: 人, 小鼠, 大鼠 WB, ELISA, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6992021
发货至: 中国
  • 抗原 See all MFN1 抗体
    MFN1 (Mitofusin 1 (MFN1))
    抗原表位
    • 16
    • 6
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 20-70, N-Term
    适用
    • 46
    • 29
    • 27
    • 21
    • 16
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 57
    • 7
    • 3
    • 1
    克隆类型
    • 52
    • 16
    多克隆
    标记
    • 36
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MFN1 antibody is un-conjugated
    应用范围
    • 50
    • 21
    • 16
    • 14
    • 6
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunocytochemistry (ICC)
    特异性
    MFN1 antibody is human, mouse and rat reactive. MFN1 antibody is predicted to not cross-react with MFN2.
    纯化方法
    MFN1 antibody is affinity chromatography purified via peptide column.
    免疫原
    MFN1 antibody was raised against a 17 amino acid peptide near the amino terminus of human MFN1. The immunogen is located within amino acids 20 - 70 of MFN1.
    亚型
    IgG
    Top Product
    Discover our top product MFN1 Primary Antibody
  • 应用备注
    MFN1 antibody can be used for detection of MFN1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunocytochemistry at 5 μ,g/mL.

    Antibody validated: Western Blot in human samples and Immunocytochemistry in human samples. All other applications and species not yet tested.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    MFN1 antibody is supplied in PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,4 °C
    储存方法
    MFN1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
  • 抗原
    MFN1 (Mitofusin 1 (MFN1))
    别名
    MFN1 (MFN1 产品)
    背景
    Mitofusin 1 (MFN1) and the related protein MFN2 are mitochondrial membrane GTPase proteins that play a central role in mitochondrial metabolism and may be associated with obesity and/or apoptosis processes (1,2). MFN1 and MFN2 form homotypic and heterotypic complexes and coordinately regulate mitochondrial fusion and are essential for embryonic development (3). When ectopically expressed, MFN1 inhibits the apoptosis-associated amino-terminal conformation change in the apoptotic protein Bax but not its mitochondrial translocation, indicating that MFN1 is involved in the regulating the activation of Bax on the outer mitochondrial membrane (4).
    分子量
    Predicted: 82 kDa

    Observed: 83 kDa
    基因ID
    55669
    NCBI登录号
    NP_284941
    UniProt
    Q8IWA4
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