ME1 抗体 (N-Term)
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北京 101111
Quick Overview for ME1 抗体 (N-Term) (ABIN6991979)
抗原
See all ME1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- ME1 antibody is human, mouse and rat reactive. ME1 antibody is predicted not to cross-react with ME2.
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纯化方法
- ME1 antibody is affinity chromatography purified via peptide column.
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免疫原
- ME1 antibody was raised against a 16 amino acid peptide near the amino terminus of human ME1. The immunogen is located within the first 50 amino acids of ME1.
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亚型
- IgG
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应用备注
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ME1 antibody can be used for detection of ME1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry at 5 μ,g/mL.
Antibody validated: Western Blot in human samples and Immunohistochemistry in mouse samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- ME1 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- ME1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- ME1 (Malic Enzyme 1, NADP(+)-Dependent, Cytosolic (ME1))
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别名
- ME1
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背景
- ME1, also known as NADP-ME, MES or HUMNDME, may play an important role as a housekeeping protein within the cell (1). ME1 is a 572 amino acid cytoplasmic protein that belongs to the malic enzyme family (2). It is expressed ubiquitously with highest expression in liver and white adipose tissue. ME1 functions as an NADP-dependent enzyme that generates NADPH for fatty acid biosynthesis (3). The activity of this enzyme, the reversible oxidative decarboxylation of malate, links the glycolytic and citric acid cycles (3,4). ME1 is regulated by both thyroid hormone levels and the amount of carbohydrates in the diet (5).
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分子量
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Predicted: 63 kDa
Observed: 63 kDa -
基因ID
- 4199
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NCBI登录号
- NP_002386
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UniProt
- P48163
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途径
- Regulation of Lipid Metabolism by PPARalpha
抗原
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