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FMR1 抗体 (C-Term)

This anti-FMR1 antibody is a 兔 多克隆 antibody detecting FMR1 in WB, ELISA, IF 和 IHC (p). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6991972
发货至: 中国

Quick Overview for FMR1 抗体 (C-Term) (ABIN6991972)

抗原

See all FMR1 抗体
FMR1 (Fragile X Mental Retardation 1 (FMR1))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This FMR1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    C-Term

    特异性

    FMR1 antibody is human, mouse and rat reactive. Multiple isoforms of FMR1 are known to exist.

    纯化方法

    FMR1 antibody is affinity chromatography purified via peptide column.

    免疫原

    FMR1 antibody was raised against a 19 amino acid peptide near the carboxy terminus of human FMR1. The immunogen is located within the last 50 amino acids of FMR1.

    亚型

    IgG
  • 应用备注

    FMR1 antibody can be used for detection of FMR1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in rat samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    FMR1 antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,4 °C

    储存方法

    FMR1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
  • 抗原

    FMR1 (Fragile X Mental Retardation 1 (FMR1))

    别名

    FMR1

    背景

    Fragile X syndrome is a frequent form of inherited mental retardation caused by functional loss of the fragile X mental retardation protein, FMR1, also known as FMRP (1). FMR1 binds RNA and is associated with polysomes. The encoded protein may be involved in mRNA trafficking from the nucleus to the cytoplasm (2). A trinucleotide repeat (CGG) in the 5' UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome (1). Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure (POF1) (3).

    分子量

    Predicted: 70 kDa

    Observed: 74 kDa

    基因ID

    2332

    NCBI登录号

    NP_002015

    UniProt

    Q06787

    途径

    Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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