GRK6 抗体 (C-Term)
Quick Overview for GRK6 抗体 (C-Term) (ABIN6991952)
抗原
See all GRK6 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- GRK6 antibody is human, mouse and rat reactive. Multiple isoforms of GRK6 are known to exist. This antibody is predicted to not cross-react with other members of the GRK protein family.
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纯化方法
- GRK6 antibody is affinity chromatography purified via peptide column.
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免疫原
- GRK6 antibody was raised against a 19 amino acid peptide near the carboxy terminus of human GRK6. The immunogen is located within the last 50 amino acids of GRK6.
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亚型
- IgG
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anti-G Protein-Coupled Receptor Kinase 6 (GRK6) (AA 71-170) antibody
GRK6 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2G1 unconjugated
anti-G Protein-Coupled Receptor Kinase 6 (GRK6) (AA 382-417), (C-Term) antibodyGRK6 适用: 人, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor Kinase 6 (GRK6) (AA 71-170) antibodyGRK6 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 8D4 unconjugated
anti-G Protein-Coupled Receptor Kinase 6 (GRK6) (AA 71-170) antibodyGRK6 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2C3 unconjugated
anti-G Protein-Coupled Receptor Kinase 6 (GRK6) (N-Term) antibodyGRK6 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor Kinase 6 (GRK6) (AA 1-170) antibodyGRK6 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor Kinase 6 (GRK6) (AA 1-170) antibodyGRK6 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor Kinase 6 (GRK6) (AA 1-589) antibodyGRK6 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor Kinase 6 (GRK6) (N-Term) antibodyGRK6 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor Kinase 6 (GRK6) (AA 186-448) antibodyGRK6 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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GRK6 antibody can be used for detection of GRK6 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in rat samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- GRK6 antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- GRK6 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- GRK6 (G Protein-Coupled Receptor Kinase 6 (GRK6))
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别名
- GRK6
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背景
- The G protein-coupled receptor kinases (GRKs) are a versatile family of kinases that play a critical role in cancer metastasis through their regulation of G-protein coupled receptors (GPCRs) involved in growth factor mediated cell migration (1,2). Phosphorylation of receptors by GRKs appears to be strictly dependent on the receptor being in its agonist-activated state (1). GRK6 is one of 7 members of the GRK serine/threonine kinase subfamily, which has been shown to modulate the Wnt signaling pathway via phosphorylation of LRP6 (3,4), and the insulin-like growth factor signaling pathway (4). GRK6 may also play a role in immune system function (5).
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分子量
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Predicted: 63 kDa
Observed: 63 kDa -
基因ID
- 2870
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NCBI登录号
- NP_001004106
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UniProt
- P43250
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途径
- Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events, Negative Regulation of Transporter Activity
抗原
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