CXCL12 抗体
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北京 101111
Quick Overview for CXCL12 抗体 (ABIN6991936)
抗原
See all CXCL12 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- CXCL12 antibody is human and mouse reactive. Multiple isoforms of CXCL12 are known to exist.
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纯化方法
- CXCL12 antibody is affinity chromatography purified via peptide column.
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免疫原
- CXCL12 antibody was raised against a 16 amino acid peptide near the center of human CXCL12 . The immunogen is located within the last 50 amino acids of CXCL12.
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亚型
- IgG
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应用备注
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CXCL12 antibody can be used for detection of CXCL12 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunocytochemistry starting at 5 μ,g/mL.
Antibody validated: Western Blot in human samples and Immunocytochemistry in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- CXCL12 antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- CXCL12 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- CXCL12 (Chemokine (C-X-C Motif) Ligand 12 (CXCL12))
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别名
- CXCL12
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背景
- The CXCL12 protein, also known as SDF1, is a stromal cell-derived alpha chemokine member of the intercrine family. CXCL12 functions as the ligand for the G-protein coupled receptor, chemokine (C-X-C motif) receptor 4 (CXCR4) and CXCR7, and plays a role in many diverse cellular functions, including embryogenesis, immune surveillance, inflammation response, tissue homeostasis, and tumor growth and metastasis (reviewed in 1). Mutations in this gene are associated with resistance to human immunodeficiency virus type 1 infections (2).
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分子量
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Predicted: 15 kDa
Observed: 18 kDa -
基因ID
- 6387
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NCBI登录号
- NP_001171605
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UniProt
- P48061
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途径
- Regulation of Cell Size, CXCR4-mediated Signaling Events, Negative Regulation of intrinsic apoptotic Signaling
抗原
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