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CXCL12 抗体

This anti-CXCL12 antibody is a 兔 多克隆 antibody detecting CXCL12 in WB, ELISA 和 ICC. Suitable for 人 和 小鼠.
产品编号 ABIN6991936
发货至: 中国

Quick Overview for CXCL12 抗体 (ABIN6991936)

抗原

See all CXCL12 抗体
CXCL12 (Chemokine (C-X-C Motif) Ligand 12 (CXCL12))

适用

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人, 小鼠

宿主

  • 77
  • 12
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  • 1
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克隆类型

  • 80
  • 22
多克隆

标记

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This CXCL12 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunocytochemistry (ICC)
  • 特异性

    CXCL12 antibody is human and mouse reactive. Multiple isoforms of CXCL12 are known to exist.

    纯化方法

    CXCL12 antibody is affinity chromatography purified via peptide column.

    免疫原

    CXCL12 antibody was raised against a 16 amino acid peptide near the center of human CXCL12 . The immunogen is located within the last 50 amino acids of CXCL12.

    亚型

    IgG
  • 应用备注

    CXCL12 antibody can be used for detection of CXCL12 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunocytochemistry starting at 5 μ,g/mL.

    Antibody validated: Western Blot in human samples and Immunocytochemistry in human samples. All other applications and species not yet tested.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    CXCL12 antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,4 °C

    储存方法

    CXCL12 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
  • 抗原

    CXCL12 (Chemokine (C-X-C Motif) Ligand 12 (CXCL12))

    别名

    CXCL12

    背景

    The CXCL12 protein, also known as SDF1, is a stromal cell-derived alpha chemokine member of the intercrine family. CXCL12 functions as the ligand for the G-protein coupled receptor, chemokine (C-X-C motif) receptor 4 (CXCR4) and CXCR7, and plays a role in many diverse cellular functions, including embryogenesis, immune surveillance, inflammation response, tissue homeostasis, and tumor growth and metastasis (reviewed in 1). Mutations in this gene are associated with resistance to human immunodeficiency virus type 1 infections (2).

    分子量

    Predicted: 15 kDa

    Observed: 18 kDa

    基因ID

    6387

    NCBI登录号

    NP_001171605

    UniProt

    P48061

    途径

    Regulation of Cell Size, CXCR4-mediated Signaling Events, Negative Regulation of intrinsic apoptotic Signaling
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