ULK3 抗体 (AA 230-280)
Quick Overview for ULK3 抗体 (AA 230-280) (ABIN6991934)
抗原
See all ULK3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 230-280
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特异性
- ULK3 antibody is human specific. Multiple isoforms of ULK3 are known to exist.
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纯化方法
- ULK3 antibody is affinity chromatography purified via peptide column.
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免疫原
- ULK3 antibody was raised against a 19 amino acid peptide near the center of human ULK3. The immunogen is located within amino acids 230 - 280 of ULK3.
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亚型
- IgG
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anti-Unc-51-Like Kinase 3 (ULK3) (AA 435-468), (C-Term) antibody
ULK3 适用: 人, 小鼠, 大鼠 WB 宿主: 小鼠 Monoclonal 1404CT148-89-25 unconjugated
anti-Unc-51-Like Kinase 3 (ULK3) (Internal Region) antibodyULK3 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Unc-51-Like Kinase 3 (ULK3) antibodyULK3 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated
anti-Unc-51-Like Kinase 3 (ULK3) (AA 427-454), (C-Term) antibodyULK3 适用: 人, 小鼠, 大鼠 WB, IHC, ICC, FACS, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Unc-51-Like Kinase 3 (ULK3) (AA 14-43), (N-Term) antibodyULK3 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB12633 unconjugated
anti-Unc-51-Like Kinase 3 (ULK3) antibodyULK3 适用: 人, 小鼠, 大鼠 WB 宿主: 小鼠 Monoclonal 4C5 unconjugated
anti-Unc-51-Like Kinase 3 (ULK3) (AA 44-240) antibodyULK3 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Unc-51-Like Kinase 3 (ULK3) (AA 1-214) antibodyULK3 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Unc-51-Like Kinase 3 (ULK3) (AA 445-458) antibodyVerified ULK3 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Unc-51-Like Kinase 3 (ULK3) (C-Term) antibodyVerified ULK3 适用: 人 ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
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应用备注
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ULK3 antibody can be used for detection of ULK3 by Western blot at 0.5 - 1 μ,g/mL. Antibody can also be used for Immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- ULK3 antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- ULK3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- ULK3 (Unc-51-Like Kinase 3 (ULK3))
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别名
- ULK3
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背景
- ULK3 belongs to the Ser/Thr protein kinase superfamily and plays a role in the ATP-dependent phosphorylation of target proteins (1). Knockout of ULK genes results in a severe defect in the autophagy pathway (2). ULK3, like the other Unc-51-like kinases such as ULK1, ULK2 and ULK4, is highly conserved among eukaryotes (3). ULK3 has been shown to be a positive regulator of the Hedgehog signaling pathway by enhancing GLI1 and GLI2 transcriptional activity (4). Furthermore, ULK3 can also interact with SUFU, a protein required for the negative regulation of GLI proteins, this interaction blocks the autophosphorylation of ULK3 and blocks its ability to regulate the GLI proteins (5).
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分子量
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Predicted: 52 kDa
Observed: 52 kDa -
基因ID
- 25989
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NCBI登录号
- NP_001092906
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UniProt
- Q6PHR2
抗原
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