MAP1LC3A 抗体 (N-Term)
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Quick Overview for MAP1LC3A 抗体 (N-Term) (ABIN6991931)
抗原
See all MAP1LC3A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- MAP1LC3A antibody is human specific. At least two isoforms of MAP1LC3A are known to exist. MAP1LC3A antibody is predicted to not cross-react with MAP1LC3B or MAP1LC3C.
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纯化方法
- MAP1LC3A antibody is affinity chromatography purified via peptide column.
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免疫原
- MAP1LC3A antibody was raised against a 10 amino acid peptide near the amino terminus of human MAP1LC3A. The immunogen is located within the first 50 amino acids of MAP1LC3A.
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亚型
- IgG
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应用备注
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MAP1LC3A antibody can be used for detection of MAP1LC3A by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- MAP1LC3A antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- MAP1LC3A antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- MAP1LC3A (Microtubule-Associated Protein 1 Light Chain 3 alpha (MAP1LC3A))
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别名
- MAP1LC3A
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背景
- Microtubule-associated proteins (MAPs) regulate microtubule stability and play critical roles in neuronal development and plasticity (1). MAP1LC3A belongs to the MAP1 LC3 family of proteins that form mature complexes with MAP1A and MAP1B which are thought to be important in the formation and development of axons and dendrites (2). MAP1LC3A is one of three isoforms of MAP1LC3, the mammalian homolog of yeast ATG8, an essential autophagy protein. These isoforms exhibit distinct expression patterns and MAP1LC3A, like MAP1LC3A but not MAP1LC3B, is post-translationally modified, suggesting the three isoforms may have different physiological functions (3).
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分子量
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Predicted: 14 kDa
Observed: 17 kDa -
基因ID
- 84557
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NCBI登录号
- NP_852610
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UniProt
- Q9H492
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途径
- Autophagy
抗原
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