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KDM1B 抗体 (N-Term)

This anti-KDM1B antibody is a 兔 多克隆 antibody detecting KDM1B in ELISA 和 WB. Suitable for 人 和 小鼠.
产品编号 ABIN6991923
发货至: 中国

Quick Overview for KDM1B 抗体 (N-Term) (ABIN6991923)

抗原

See all KDM1B 抗体
KDM1B (Lysine (K)-Specific Demethylase 1B (KDM1B))

适用

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人, 小鼠

宿主

  • 40
  • 9

克隆类型

  • 35
  • 14
多克隆

标记

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This KDM1B antibody is un-conjugated

应用范围

  • 21
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  • 13
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  • 9
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  • 4
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ELISA, Western Blotting (WB)
  • 抗原表位

    • 15
    • 6
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    • 2
    • 1
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    • 1
    • 1
    AA 80-130, N-Term

    特异性

    KDM1B antibody is human, mouse and rat reactive. At least two isoforms of KDM1B are known to exist, this KDM1B antibody will detect both isoforms.

    纯化方法

    KDM1B antibody is affinity chromatography purified via peptide column.

    免疫原

    KDM1B antibody was raised against a 17 amino acid peptide near the amino terminus of human KDM1B. The immunogen is located within amino acids 80 - 130 of KDM1B.

    亚型

    IgG
  • 应用备注

    KDM1B antibody can be used for detection of KDM1B by Western blot at 0.5 μ,g/mL.

    Antibody validated: Western Blot in human samples. All other applications and species not yet tested.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    KDM1B antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,4 °C

    储存方法

    KDM1B antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
  • 抗原

    KDM1B (Lysine (K)-Specific Demethylase 1B (KDM1B))

    别名

    KDM1B

    背景

    Flavin-dependent histone demethylases regulate histone lysine methylation, an epigenetic mark that regulates gene expression and chromatin function (reviewed in 1). KDM1B is a recently identified histone H3K4 demethylase that is required to establish maternal genomic imprints, targeted disruption of the KDM1B gene in mice led to lethality in their embryos, suggesting demethylation of H3K4 is critical for establishing the DNA methylation imprints (2). KDM1B has also been shown to play a role in the transcription elongation in several genes (3).

    分子量

    Predicted: 90 kDa

    Observed: 90 kDa

    基因ID

    221656

    NCBI登录号

    NP_694587

    UniProt

    Q8NB78

    途径

    Warburg Effect
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