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IL36A/IL1F6 抗体 (C-Term)

This anti-IL36A/IL1F6 antibody is a 兔 多克隆 antibody detecting IL36A/IL1F6 in WB, ELISA, IF 和 IHC (p). Suitable for 人.
产品编号 ABIN6991915
发货至: 中国

Quick Overview for IL36A/IL1F6 抗体 (C-Term) (ABIN6991915)

抗原

See all IL36A/IL1F6 (IL1F6) 抗体
IL36A/IL1F6 (IL1F6) (Interleukin 1 Family, Member 6 (IL1F6))

适用

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宿主

  • 40
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克隆类型

  • 42
  • 3
多克隆

标记

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This IL36A/IL1F6 antibody is un-conjugated

应用范围

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  • 18
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  • 5
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Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 8
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    • 2
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    C-Term

    特异性

    IL-36A antibody is human specific. IL-36A antibody will not cross-react with IL-36B or IL-36G.

    纯化方法

    IL-36A antibody is affinity chromatography purified via peptide column.

    免疫原

    IL-36A antibody was raised against an 11 amino acid peptide near the carboxy terminus of human IL-36A. The immunogen is located within the last 50 amino acids of IL-36A.

    亚型

    IgG
  • 应用备注

    IL-36A antibody can be used for detection of IL-36A by Western blot at 1 - 2 μ,g/mL.

    Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    IL-36A antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,4 °C

    储存方法

    IL-36A antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
  • 抗原

    IL36A/IL1F6 (IL1F6) (Interleukin 1 Family, Member 6 (IL1F6))

    别名

    IL-36A

    背景

    IL-36A is is a member of the interleukin 1 cytokine family whose gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2 (1). IL-36A is thought to activate the NF-kappaB pathway through IL-1 receptor family members IL-1RL2 and IL-1RAcP (2). Like the related proteins IL-36B and IL-36G, IL-36A requires post-translational processing for full agonist activity, but the cleavage mechanism is currently unknown (3). The IL-36 cytokines have been suggested to amplify Th1 responses by enhancing proliferation and Th1 polarization of naive CD4+ T cells (4).

    分子量

    Predicted: 17 kDa

    Observed: 16 kDa

    基因ID

    27179

    NCBI登录号

    NP_055255

    UniProt

    Q9UHA7

    途径

    Cancer Immune Checkpoints
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