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UNG 抗体 (C-Term)

UNG 适用: 人, 小鼠 WB, ELISA, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6991909
发货至: 中国
  • 抗原 See all UNG 抗体
    UNG (Uracil-DNA Glycosylase (UNG))
    抗原表位
    • 5
    • 5
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 46
    • 25
    • 22
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 39
    • 7
    克隆类型
    • 41
    • 5
    多克隆
    标记
    • 35
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This UNG antibody is un-conjugated
    应用范围
    • 32
    • 15
    • 13
    • 10
    • 10
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    UNG1 Antibody is affinity chromatography purified via peptide column.
    免疫原
    Anti-UNG1 antibody was raised against a peptide corresponding to 13 amino acids near the carboxy terminus of human UNG1. The immunogen is located within the last 50 amino acids of UNG1.
    亚型
    IgG
    Top Product
    Discover our top product UNG Primary Antibody
  • 应用备注
    WB: 0.5-4 μ,g/mL, IHC: 2 μ,g/mL, IF: 20 μ,g/mL.

    Antibody validated: Western Blot in human and mouse samples, Immunohistochemistry in human samples, Immunofluorescence in human samples. All other applications and species not yet tested.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    UNG1 Antibody is supplied in PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,4 °C
    储存方法
    UNG1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原
    UNG (Uracil-DNA Glycosylase (UNG))
    别名
    UNG1 (UNG 产品)
    别名
    DGU antibody, HIGM4 antibody, HIGM5 antibody, UDG antibody, UNG1 antibody, UNG15 antibody, UNG2 antibody, ung antibody, zgc:56102 antibody, PSPTO4236 antibody, BA5648 antibody, ECK2578 antibody, JW2564 antibody, An02g14790 antibody, AO090001000732 antibody, DDBDRAFT_0204444 antibody, DDBDRAFT_0214910 antibody, DDB_0204444 antibody, DDB_0214910 antibody, uracil-DNA glycosylase antibody, uracil DNA glycosylase antibody, uracil DNA glycosylase a antibody, uracil-DNA glycosylase Ung antibody, uracil-DNA-glycosylase antibody, uracil DNA glycosylase L homeolog antibody, uracil glycosylase antibody, temporal expression: early antibody, ung antibody, ung2 antibody, Ung antibody, UNG antibody, unga antibody, STY2840 antibody, ung.L antibody, ANI_1_3358024 antibody, AOR_1_1318164 antibody, uglA antibody, Arnit_2731 antibody, D4R antibody
    物质类
    Viral Protein
    背景
    UNG1 Antibody: The human uracil-DNA glycosylase (UNG) gene encodes both mitochondrial (UNG1) and nuclear (UNG2) forms through differentially regulated promotes and alternative splicing. While UNG2 is the major enzyme in the base excision repair pathway that removes uracil residues from nuclear DNA that arise through either misincorporation during replication or cytosine deamination, inhibition of UNG1 by uracil glycosylase inhibitor did not lead to increased levels of spontaneous or induced mitochondrial DNA mutations. However, decreased levels of UNG activity and increased oxidative damage to mitochondrial DNA were seen in older mice, suggesting that mitochondrial DNA repair mechanisms may be involved in various neurodegenerative disorders in an age-dependent manner. This UNG1 antibody will not cross-react with UNG2.
    分子量
    Predicted: 34kD

    Observed: 34 kD kDa
    基因ID
    7374
    NCBI登录号
    NP_003353
    UniProt
    P13051
    途径
    DNA Damage Repair, Production of Molecular Mediator of Immune Response
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