TMEM107 抗体 (N-Term)
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北京 101111
Quick Overview for TMEM107 抗体 (N-Term) (ABIN6991906)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 20-70, N-Term
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特异性
- TMEM107 antibody is human specific. At least two isoforms of TMEM107 are known to exist.
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纯化方法
- TMEM107 Antibody is affinity chromatography purified via peptide column.
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免疫原
- TMEM107 antibody was raised against a 19 amino acid peptide near the amino terminus of human TMEM107. The immunogen is located within amino acids 20 - 70 of TMEM107 .
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亚型
- IgG
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应用备注
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TMEM107 antibody can be used for detection of TMEM107 by Western blot at 1 - 2 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- TMEM107 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- TMEM107antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- TMEM107 (Transmembrane Protein 107 (TMEM107))
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别名
- TMEM107
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背景
- Transmembrane protein 107 (TMEM 107) is critical for cilia formation and embryonic patterning (1). It is a 139 amino acid transmembrane protein encoded by a gene that maps to human chromosome 17 which is associated with two key tumor suppressor genes p53 and BRCA1 (1,2). TMEM107 is required for normal Sonic hedgehog (Shh) signaling in the neural tube and acts in combination with Gli2 and Gli3 to pattern ventral and intermediate neuronal cell types (1,3). TMEM107 is also a strong candidate gene for central areolar choroidal dystrophy (CACD) (1-3).
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分子量
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Predicted: 16 kDa
Observed: 19kDa -
基因ID
- 84314
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NCBI登录号
- NP_115730
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UniProt
- Q6UX40
抗原
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