T-Bet 抗体 (C-Term)
Quick Overview for T-Bet 抗体 (C-Term) (ABIN6991904)
抗原
See all T-Bet 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- TBX21 antibody is human and mouse reactive.
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纯化方法
- TBX21 Antibody is affinity chromatography purified via peptide column.
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免疫原
- TBX21 antibody was raised against a 19 amino acid peptide near the carboxy terminus of human TBX2. The immunogen is located within the last 50 amino acids of TBX21 .
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亚型
- IgG
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应用备注
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TBX21 antibody can be used for detection of TBX21 by Western blot at 1 - 2 μ,g/mL.
Antibody validated: Western Blot in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- TBX21 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- TBX21 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- T-Bet
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别名
- TBX21
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背景
- TBX21 is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box (1,2). Members of this family include transcription factors involved in the regulation of developmental processes (2). Studies in mouse and humans show that TBX21 is a Th1 cell-specific transcription factor that controls the expression of the hallmark Th1 cytokine, interferon-gamma (1,3). Expression of the human ortholog also correlates with interferon-gamma expression in Th1 and natural killer cells, suggesting a TBX21 may play a role in initiating Th1 lineage development from naive Th precursor cells. (3).
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分子量
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Predicted: 59 kDa
Observed: 55kDa -
基因ID
- 30009
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NCBI登录号
- NP_037483
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UniProt
- Q9UL17
抗原
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