BTLA 抗体 (AA 170-220)
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北京 101111
Quick Overview for BTLA 抗体 (AA 170-220) (ABIN6991902)
抗原
See all BTLA 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 170-220
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特异性
- BTLA antibody is human specific. At least two isoforms of BTLA are known to exist.
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纯化方法
- BTLA Antibody is affinity chromatography purified via peptide column.
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免疫原
- BTLA antibody was raised against a 17 amino acid peptide near the center of human BTLA. The immunogen is located within amino acids 170 - 220 of BTLA .
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亚型
- IgG
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应用备注
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BTLA antibody can be used for detection of BTLA by Western blot at 1 - 2 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- BTLA Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- BTLA antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- BTLA (B and T Lymphocyte Associated (BTLA))
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别名
- BTLA
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背景
- The B- and T-lymphocyte attenuator (BTLA) protein is a member of the immunoglobulin superfamily containing a single immunoglobulin (Ig) domain (1). Like other coihibitory receptors such as CTLA-4 and PD-1, BTLA functions as a receptor that relays inhibitory signals to suppress the immune response, and can inhibit LPS-induced endotoxic shock by suppressing TLR4 signaling in innate immune cells (1,2). Polymorphisms in this gene have also been associated with an increased risk of rheumatoid arthritis (3).
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分子量
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Predicted: 32 kDa
Observed: 40kDa -
基因ID
- 151888
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NCBI登录号
- NP_861445
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UniProt
- Q7Z6A9
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途径
- Cancer Immune Checkpoints
抗原
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