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BTLA 抗体 (AA 170-220)

This anti-BTLA antibody is a 兔 多克隆 antibody detecting BTLA in WB, ELISA, IF 和 IHC (p). Suitable for 人.
产品编号 ABIN6991902
发货至: 中国

Quick Overview for BTLA 抗体 (AA 170-220) (ABIN6991902)

抗原

See all BTLA 抗体
BTLA (B and T Lymphocyte Associated (BTLA))

适用

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宿主

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克隆类型

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多克隆

标记

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This BTLA antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
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    AA 170-220

    特异性

    BTLA antibody is human specific. At least two isoforms of BTLA are known to exist.

    纯化方法

    BTLA Antibody is affinity chromatography purified via peptide column.

    免疫原

    BTLA antibody was raised against a 17 amino acid peptide near the center of human BTLA. The immunogen is located within amino acids 170 - 220 of BTLA .

    亚型

    IgG
  • 应用备注

    BTLA antibody can be used for detection of BTLA by Western blot at 1 - 2 μ,g/mL.

    Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    BTLA Antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,4 °C

    储存方法

    BTLA antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
  • 抗原

    BTLA (B and T Lymphocyte Associated (BTLA))

    别名

    BTLA

    背景

    The B- and T-lymphocyte attenuator (BTLA) protein is a member of the immunoglobulin superfamily containing a single immunoglobulin (Ig) domain (1). Like other coihibitory receptors such as CTLA-4 and PD-1, BTLA functions as a receptor that relays inhibitory signals to suppress the immune response, and can inhibit LPS-induced endotoxic shock by suppressing TLR4 signaling in innate immune cells (1,2). Polymorphisms in this gene have also been associated with an increased risk of rheumatoid arthritis (3).

    分子量

    Predicted: 32 kDa

    Observed: 40kDa

    基因ID

    151888

    NCBI登录号

    NP_861445

    UniProt

    Q7Z6A9

    途径

    Cancer Immune Checkpoints
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