FHIT Antibody is affinity chromatography purified via peptide column.
免疫原
FHIT antibody was raised against an 18 amino acid peptide near the carboxy terminus of human FHIT. The immunogen is located within the last 50 amino acids of FHIT .
FHIT antibody can be used for detection of FHIT by Western blot at 1 - 2 μ,g/mL.
Antibody validated: Western Blot in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
限制
仅限研究用
状态
Liquid
浓度
1 mg/mL
缓冲液
FHIT Antibody is supplied in PBS containing 0.02 % sodium azide.
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
-20 °C,4 °C
储存方法
FHIT antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
抗原
FHIT
(Fragile Histidine Triad (FHIT))
别名
FHIT
背景
FHIT is member of the histidine triad gene family and is a diadenosine involved in purine metabolism (1). FHIT is also thought to be a tumor suppressor gene and is involved in multiple apoptotic pathways (1,2). The FHIT gene encompasses the common fragile site FRA3B on chromosome 3, where carcinogen-induced damage can lead to translocations and aberrant transcripts of this gene (3). Aberrant transcripts from this gene have been found in multiple carcinomas (4).