DDC 抗体 (C-Term)
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北京 101111
Quick Overview for DDC 抗体 (C-Term) (ABIN6991892)
抗原
See all DDC 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 390-440, C-Term
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特异性
- DDC antibody is human, mouse and rat reactive.
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纯化方法
- DDC Antibody is affinity chromatography purified via peptide column.
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免疫原
- DDC antibody was raised against a 14 amino acid peptide near the carboxy terminus of human DDC. The immunogen is located within amino acids 390 - 440 of DDC .
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亚型
- IgG
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应用备注
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DDC antibody can be used for detection of DDC by Western blot at 1 - 2 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- DDC Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- DDC antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- DDC (Dopa Decarboxylase (Aromatic L-Amino Acid Decarboxylase) (DDC))
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别名
- DDC
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背景
- DOPA decarboxylase (DDC) belongs to the group II decarboxylase family of proteins (1). It is an important protein in the catecholamine biosynthesis pathway. DDC catalyzes the second reaction in the biosynthesis of catecholamines, trace amines and serotonin (1,2). It can form a homodimer and is expressed in the central nervous system (2). DDC can be used as markers for dopaminergic, noradrenergic and serotonergic neurons in a variety of applications including depression, schizophrenia, Parkinson's disease, neuroendocrine tumors and drug abuse (3,4). Defects in DDC gene may cause the autosomal recessive disorder AADC deficiency (4).
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分子量
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Predicted: 53 kDa
Observed: 53 kDa -
基因ID
- 1644
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NCBI登录号
- NP_000781
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UniProt
- P20711
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途径
- Dopaminergic Neurogenesis
抗原
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