NCBP1 抗体 (AA 420-470)
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北京 101111
Quick Overview for NCBP1 抗体 (AA 420-470) (ABIN6991877)
抗原
See all NCBP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 420-470
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特异性
- NCBP1 antibody is human, mouse and rat reactive. At least two isoforms of NCBP1 are known to exist, this antibody will detect both isoforms of NCBP1.
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纯化方法
- NCBP1 Antibody is affinity chromatography purified via peptide column.
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免疫原
- NCBP1 antibody was raised against a 17 amino acid peptide near the center of human NCBP1. The immunogen is located within amino acids 420 - 470 of NCBP1.
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亚型
- IgG
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应用备注
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NCBP1 antibody can be used for detection of NCBP1 by Western blot at 1 - 2 μ,g/mL.
Antibody validated: Western Blot in human samples and Immunocytochemistry in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- NCBP1 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- NCBP1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- NCBP1 (Nuclear Cap Binding Protein Subunit 1, 80kDa (NCBP1))
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别名
- NCBP1
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背景
- NCBP1 Antibody: NCBP1, also known as CBP80, is a component of the nuclear cap-binding protein complex (CBC), which binds to the monomethylated 5' cap of nascent pre-mRNA in the nucleoplasm. NCBP1 promotes high-affinity mRNA-cap binding and associates with the CTD of RNA polymerase II. The CBC promotes pre-mRNA splicing, 3'-end processing, RNA nuclear export, and nonsense-mediated mRNA decay (1,2). Recent evidence has shown that cellular-cap-binding proteins such as NCBP1 associate with influenza virus mRNAs, suggesting that these viral mRNAs may follow the normal cellular pathways for splicing, nuclear export, and translation (3).
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分子量
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Predicted: 87 kDa
Observed: 87 kDa -
基因ID
- 4686
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NCBI登录号
- NP_002477
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UniProt
- Q09161
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途径
- Ribonucleoprotein Complex Subunit Organization, Photoperiodism, Methionine Biosynthetic Process
抗原
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