NCBP1 抗体 (C-Term)
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北京 101111
Quick Overview for NCBP1 抗体 (C-Term) (ABIN1881565)
抗原
See all NCBP1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 647-675, C-Term
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预测反应
- M, Rat
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This NCBP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 647-675 amino acids from the C-terminal region of human NCBP1.
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亚型
- Ig Fraction
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anti-Nuclear Cap Binding Protein Subunit 1, 80kDa (NCBP1) (AA 1-790) antibody
NCBP1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Nuclear Cap Binding Protein Subunit 1, 80kDa (NCBP1) (N-Term) antibodyNCBP1 适用: 人 WB, IHC (p), IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Cap Binding Protein Subunit 1, 80kDa (NCBP1) (N-Term) antibodyNCBP1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Cap Binding Protein Subunit 1, 80kDa (NCBP1) (AA 2-99) antibodyNCBP1 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1E9 unconjugated
anti-Nuclear Cap Binding Protein Subunit 1, 80kDa (NCBP1) (N-Term) antibodyNCBP1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Cap Binding Protein Subunit 1, 80kDa (NCBP1) (N-Term) antibodyNCBP1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Cap Binding Protein Subunit 1, 80kDa (NCBP1) (AA 2-100) antibodyNCBP1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1E9 unconjugated
anti-Nuclear Cap Binding Protein Subunit 1, 80kDa (NCBP1) (N-Term) antibodyNCBP1 适用: 人, Cow, 犬, 兔, Pig, 非洲爪蟾, 猴 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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: "UPF1 association with the cap-binding protein, CBP80, promotes nonsense-mediated mRNA decay at two distinct steps." in: Molecular cell, Vol. 39, Issue 3, pp. 396-409, (2010) (PubMed).
: "A new MIF4G domain-containing protein, CTIF, directs nuclear cap-binding protein CBP80/20-dependent translation." in: Genes & development, Vol. 23, Issue 17, pp. 2033-45, (2009) (PubMed).
: "The molecular basis for the regulation of the cap-binding complex by the importins." in: Nature structural & molecular biology, Vol. 16, Issue 9, pp. 930-7, (2009) (PubMed).
: "Diverse role of three tyrosines in binding of the RNA 5' cap to the human nuclear cap binding complex." in: Journal of molecular biology, Vol. 385, Issue 2, pp. 618-27, (2009) (PubMed).
: "SKAR links pre-mRNA splicing to mTOR/S6K1-mediated enhanced translation efficiency of spliced mRNAs." in: Cell, Vol. 133, Issue 2, pp. 303-13, (2008) (PubMed).
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: "UPF1 association with the cap-binding protein, CBP80, promotes nonsense-mediated mRNA decay at two distinct steps." in: Molecular cell, Vol. 39, Issue 3, pp. 396-409, (2010) (PubMed).
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- NCBP1 (Nuclear Cap Binding Protein Subunit 1, 80kDa (NCBP1))
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别名
- NCBP1
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背景
- The product of this gene is a component of the nuclear cap-binding protein complex (CBC), which binds to the monomethylated 5' cap of nascent pre-mRNA in the nucleoplasm. The encoded protein promotes high-affinity mRNA-cap binding and associates with the CTD of RNA polymerase II. The CBC promotes pre-mRNA splicing, 3'-end processing, RNA nuclear export, and nonsense-mediated mRNA decay.
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分子量
- 91839
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NCBI登录号
- NP_002477
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UniProt
- Q09161
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途径
- Ribonucleoprotein Complex Subunit Organization, Photoperiodism, Methionine Biosynthetic Process
抗原
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