GABARAP 抗体 (N-Term)
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Quick Overview for GABARAP 抗体 (N-Term) (ABIN6991865)
抗原
See all GABARAP 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- Multiple isoforms of GABARAP exist due to alternative splicing events.
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纯化方法
- GABARAP Antibody is affinity chromatography purified via peptide column.
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免疫原
- GABARAP antibody was raised against a 19 amino acid peptide near the amino terminus of human GABARAP. The immunogen is located within the first 50 amino acids of GABARAP.
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亚型
- IgG
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应用备注
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GABARAP antibody can be used for detection of GABARAP by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in mouse samples and Immunofluorescence in human and mouse samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- GABARAP Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- GABARAP antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- GABARAP (GABA(A) Receptor-Associated Protein (GABARAP))
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别名
- GABARAP
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背景
- GABARAP Antibody: Gamma-aminobutyric acid (GABA) is the main inhibitory transmitter by increasing a Cl-conductance that inhibits neuronal firing in the central nervous system. It has been shown to activate both ionotropic (GABAA) and metabotropic (GABAB) receptors as well as a third class of receptors called GABAC. GABARAP (GABAA receptor-associated protein) links GABAA receptors to the cytoskeleton and may play a role in intracellular transport of GABAA receptors and its interaction with the cytoskeleton. GABARAP belongs to the MAP1 or ATG8 like family and recent studies show that MAPK15/ERK8 is acting through interaction with ATG8 family proteins to regulate autophagy.
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分子量
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Predicted: 13kDa
Observed: 15 kDa -
基因ID
- 11337
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NCBI登录号
- NP_009209
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UniProt
- O95166
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途径
- Autophagy
抗原
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