UNG 抗体 (N-Term)
Quick Overview for UNG 抗体 (N-Term) (ABIN6991863)
抗原
See all UNG 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- At least two isoforms of UNG2 are known to exist, this antibody will only detect the longer isoform. UNG2 antibody is predicted to not cross-react with UNG1.
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纯化方法
- UNG2 Antibody is affinity chromatography purified via peptide column.
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免疫原
- UNG2 antibody was raised against a 17 amino acid peptide near the amino terminus of human UNG2. The immunogen is located within the first 50 amino acids of UNG2.
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亚型
- IgG
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anti-Uracil-DNA Glycosylase (UNG) (AA 1-313) antibody
UNG 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Uracil-DNA Glycosylase (UNG) antibodyUNG 适用: 人, 猴 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 1G2 unconjugated
anti-Uracil-DNA Glycosylase (UNG) (AA 1-304) antibodyUNG 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Uracil-DNA Glycosylase (UNG) (AA 114-224) antibodyUNG 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Uracil-DNA Glycosylase (UNG) (Internal Region) antibodyUNG 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Uracil-DNA Glycosylase (UNG) (AA 281-298) antibodyUNG 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Uracil-DNA Glycosylase (UNG) (AA 1-304) antibodyUNG 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Uracil-DNA Glycosylase (UNG) (AA 1-100) antibodyUNG 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Uracil-DNA Glycosylase (UNG) (AA 1-313) antibodyUNG 适用: 人 WB, ELISA, IF, ICC 宿主: 小鼠 Monoclonal k1C12 unconjugated
anti-Uracil-DNA Glycosylase (UNG) (N-Term) antibodyUNG 适用: 人, 小鼠 WB, ELISA, IHC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
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UNG2 antibody can be used for detection of UNG2 by Western blot at 1 - 2 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- UNG2 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- UNG2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- UNG (Uracil-DNA Glycosylase (UNG))
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别名
- UNG2
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背景
- UNG2 Antibody: The human uracil-DNA glycosylase (UNG) gene encodes both mitochondrial (UNG1) and nuclear (UNG2) forms through differentially regulated promoters and alternative splicing. UNG2 is the major enzyme in the base excision repair pathway that removes uracil residues from DNA that arise through either misincorporation during replication or cytosine deamination. UNG2 can also be bound by the HIV-1 integrase and incorporated into the virion particle, suggesting that it is required to remove uracils from the viral genome. As the intrinsic antiviral protein APOBEC3G generates numerous uracils in the HIV genome during its replication, it may be that the UNG2 contributes to the APOBEC3G-mediated loss of infectivity by generating abasic sites in the viral genome.
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分子量
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Predicted: 34 kDa
Observed: 33 kDa -
基因ID
- 7374
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NCBI登录号
- NP_550433
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UniProt
- P13051
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途径
- DNA Damage Repair, Production of Molecular Mediator of Immune Response
抗原
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