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ULK1 抗体 (AA 350-400)

This anti-ULK1 antibody is a 兔 多克隆 antibody detecting ULK1 in WB, ELISA, IF 和 IHC (p). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6991858
发货至: 中国

Quick Overview for ULK1 抗体 (AA 350-400) (ABIN6991858)

抗原

See all ULK1 抗体
ULK1 (Unc-51 Like Kinase 1 (ULK1))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This ULK1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    AA 350-400

    特异性

    Two alternatively spliced transcript variants encoding different isoforms have been identified. ULK1 antibody is predicted to not cross-react with ULK2.

    纯化方法

    ULK1 Antibody is affinity chromatography purified via peptide column.

    免疫原

    ULK1 antibody was raised against a 16 amino acid peptide near the center of human ULK1 . The immunogen is located within amino acids 350 - 400 of ULK1.

    亚型

    IgG
  • 应用备注

    ULK1 Antibody can be used for detection of ULK1 by Western blot at 1 μ,g/mL.

    Antibody validated: Western Blot in rat samples, Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    ULK1 Antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,4 °C

    储存方法

    ULK1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
  • 抗原

    ULK1 (Unc-51 Like Kinase 1 (ULK1))

    别名

    ULK1

    背景

    ULK1 Antibody: ULK1, also known as ATG1, is a key serine/threonine protein kinase probably acting at the most upstream step of autophagosome formation. Knockout of ULK1 results in a severe defect in the autophagy pathway. ULK1 is highly conserved among eukaryotes, and are the Unc-51-like kinases, ULK1 and ULK2 in mammals. ULK1 is ubiquitously expressed and involved in autophagy in response to starvation. It is the target of the TOR kinase signaling pathway that regulates autophagy through the control of phosphorylation status of ATG13. ULK1 also plays a role early in neuronal differentiation.

    分子量

    Predicted: 116 kDa

    Observed: 105 kDa

    基因ID

    8408

    NCBI登录号

    NP_003556

    UniProt

    O75385

    途径

    Regulation of Cell Size, Autophagy
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