KREMEN1 抗体 (C-Term)
Quick Overview for KREMEN1 抗体 (C-Term) (ABIN6991831)
抗原
See all KREMEN1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- Three isoforms of KREMEN1 exists as a result of alternative splicing event.
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纯化方法
- KREMEN1 Antibody is affinity chromatography purified via peptide column.
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免疫原
- Rabbit polyclonal KREMEN1 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human KREMEN1. The immunogen is located within the last 50 amino acids of KREMEN1.
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亚型
- IgG
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anti-Kringle Containing Transmembrane Protein 1 (KREMEN1) (AA 180-380) antibody
KREMEN1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Kringle Containing Transmembrane Protein 1 (KREMEN1) (AA 71-120) antibodyKREMEN1 适用: 人, 小鼠, 大鼠, 豚鼠, 兔, 犬, 斑马鱼, 猴, Bat, 小鸡, Pig, 非洲爪蟾 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Kringle Containing Transmembrane Protein 1 (KREMEN1) (AA 310-391) antibodyKREMEN1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1E7 unconjugated
anti-Kringle Containing Transmembrane Protein 1 (KREMEN1) (AA 310-391) antibodyKREMEN1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Kringle Containing Transmembrane Protein 1 (KREMEN1) (AA 108-157) antibodyKREMEN1 适用: 人, 小鼠, 大鼠, 豚鼠, 兔, Cow, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Kringle Containing Transmembrane Protein 1 (KREMEN1) (AA 180-380) antibodyKREMEN1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Kringle Containing Transmembrane Protein 1 (KREMEN1) (N-Term) antibodyKREMEN1 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Kringle Containing Transmembrane Protein 1 (KREMEN1) (AA 157-390) antibodyKREMEN1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Kringle Containing Transmembrane Protein 1 (KREMEN1) (AA 53-82), (N-Term) antibodyKREMEN1 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB10586 unconjugated
anti-Kringle Containing Transmembrane Protein 1 (KREMEN1) (N-Term) antibodyKREMEN1 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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KREMEN1 antibody can be used for detection of KREMEN1 by Western blot at 0.125 - 0.25 μ,g/mL.
Antibody validated: Western Blot in rat samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- KREMEN1 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- KREMEN1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- KREMEN1 (Kringle Containing Transmembrane Protein 1 (KREMEN1))
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别名
- KREMEN1
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背景
- KREMEN1 Antibody: Kremen (Kringle containing protein marking the eye and the nose) proteins are type I transmembrane proteins that contain extracellular kringle, WSC and CUB domains and an intracellular region without any conserved motifs. Kremens bind a subset of the secreted Dickkopf proteins (Dkk 1, 2, and 4) with high affinity to modulate the canonical Wnt signaling pathway that is transduced by the ternary receptor complex composed of Wnt, Frizzled, and the LDL receptor related protein 5/6 (LRP5/6) coreceptor. KREMEN1 is a receptor for the Dickkopf protein which blocks Wnt/beta catenin signaling. It is necessary to ensure normal spatial and temporal patterns of Wnt activity during developmental processes.
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分子量
- 54 kDa
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基因ID
- 83999
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NCBI登录号
- NP_114434
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UniProt
- Q96MU8
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途径
- WNT signaling
抗原
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