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TYK2 抗体 (N-Term)

This anti-TYK2 antibody is a 兔 多克隆 antibody detecting TYK2 in WB, ELISA 和 IF. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6991802
发货至: 中国

Quick Overview for TYK2 抗体 (N-Term) (ABIN6991802)

抗原

See all TYK2 抗体
TYK2 (Tyrosine Kinase 2 (TYK2))

适用

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人, 小鼠, 大鼠

宿主

  • 76
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克隆类型

  • 76
  • 13
多克隆

标记

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This TYK2 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF)
  • 抗原表位

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    AA 90-140, N-Term

    特异性

    At least three isoforms of TYK2 are known to exist, this antibody only detects the two longest isoforms.

    纯化方法

    TYK2 Antibody is affinity chromatography purified via peptide column.

    免疫原

    Rabbit polyclonal TYK2 antibody was raised against a 17 amino acid peptide near the amino terminus of human TYK2. The immunogen is located within amino acids 90 - 140 of TYK2.

    亚型

    IgG
  • 应用备注

    TYK2 antibody can be used for detection of TYK2 by Western blot at 1 - 2 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    TYK2 Antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,4 °C

    储存方法

    TYK2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
  • 抗原

    TYK2 (Tyrosine Kinase 2 (TYK2))

    别名

    TYK2

    背景

    TYK2 Antibody: TYK2 is a member of the Janus kinases (JAKs) protein families. TYK2 associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits and is also a component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E.

    分子量

    Predicted: 131 kDa

    基因ID

    7297

    NCBI登录号

    NP_003322

    UniProt

    P29597

    途径

    JAK/STAT Signaling, Hepatitis C
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