CRB2 抗体 (AA 460-510)
Quick Overview for CRB2 抗体 (AA 460-510) (ABIN6991796)
抗原
See all CRB2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 460-510
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特异性
- At least three isoforms of CRB2 are known to exist, this antibody will detect all three. CRB2 antibody is predicted to not cross-react with other members of the CRB family.
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纯化方法
- CRB2 Antibody is affinity chromatography purified via peptide column.
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免疫原
- Rabbit polyclonal CRB2 antibody was raised against a 17 amino acid peptide near the center of human CRB2. The immunogen is located within amino acids 460 - 510 of CRB2.
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亚型
- IgG
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anti-Crumbs Homolog 2 (CRB2) (AA 1258-1285) antibody
CRB2 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB27068 unconjugated
anti-Crumbs Homolog 2 (CRB2) (AA 701-800) antibodyCRB2 适用: 小鼠, 大鼠 ELISA, WB, IF (cc), IF (p), IHC (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
anti-Crumbs Homolog 2 (CRB2) (AA 253-483) antibodyCRB2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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CRB2 antibody can be used for detection of CRB2 by Western blot at 1 - 2 μ,g/mL.
Antibody validated: Western Blot in rat samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- CRB2 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- CRB2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- CRB2 (Crumbs Homolog 2 (CRB2))
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别名
- CRB2
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背景
- CRB2 Antibody: CRB2 (Crumbs homolog 2), like its homologs CRB1 and CRB3, is similar to the Drosophila crumbs protein and is expressed in retina, brain and kidney. Along with other proteins, the Crumbs proteins form a complex that help set up cell polarity in developing neuroepithelial cells. At the onset of neural specification, embryonic stem cells (ESCs) upregulate CRB2, which then localizes apically in neural rosettes. Gain- and loss-of-function studies of CRB2 have shown that CRB2 is essential for the stabilization of other polarity proteins. Unlike CRB1, mutations in CRB2 do not appear to play a role in retinitis pigmentosa or in Leber congenital amaurosis.
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分子量
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Predicted: 105, 129, and 141 kDa
Observed: 103, 128 kDa -
基因ID
- 286204
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NCBI登录号
- NP_775960
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UniProt
- Q5IJ48
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途径
- Notch Signaling
抗原
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