CRB1 抗体 (AA 780-830)
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北京 101111
Quick Overview for CRB1 抗体 (AA 780-830) (ABIN6991795)
抗原
See all CRB1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 780-830
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特异性
- Alternatively spliced transcript variants have been observed. CRB1 antibody i spredicted to not cross-react with CRB2.
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纯化方法
- CRB1 Antibody is affinity chromatography purified via peptide column.
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免疫原
- Rabbit polyclonal CRB1 antibody was raised against an 18 amino acid peptide near the center of human CRB1. The immunogen is located within amino acids 780 - 830 of CRB1.
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亚型
- IgG
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应用备注
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CRB1 antibody can be used for detection of CRB1 by Western blot at 1 - 2 μ,g/mL.
Antibody validated: Western Blot in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- CRB1 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- CRB1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- CRB1 (Crumbs Homolog 1 (CRB1))
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别名
- CRB1
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背景
- CRB1 Antibody: CRB1 (Crumbs homolog 1) plays a role in photoreceptor morphogenesis in the retina. It may maintain cell polarization and adhesion. CRB1 is similar to the Drosophila crumbs protein and localizes to the inner segment of mammalian photoreceptors. The first identified human homolog, CRB1, is expressed in retina and some parts of the brain, leaving room for another homolog to function in epithelial tissues. Mutations in this gene are associated with a severe form of retinitis pigmentosa, RP12, and with Leber congenital amaurosis.
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分子量
- Predicted: 142 kDa
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基因ID
- 23418
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NCBI登录号
- NP_001180569
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UniProt
- P82279
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途径
- Notch Signaling
抗原
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