ACSL1 抗体 (AA 240-290)
Our Local Distributor
北京 101111
Quick Overview for ACSL1 抗体 (AA 240-290) (ABIN6991772)
抗原
See all ACSL1 (Acsl1) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 240-290
-
特异性
- At least three isoforms of ACSL1 are known to exist, this antibody will detect all three isoforms.
-
纯化方法
- ACSL1 Antibody is affinity chromatography purified via peptide column.
-
免疫原
- Rabbit polyclonal ACSL1 antibody was raised against an 18 amino acid peptide near the center of human ACSL1. The immunogen is located within amino acids 240 - 290 of ACSL1.
-
亚型
- IgG
-
-
-
-
应用备注
-
ACSL1 antibody can be used for detection of ACSL1 by Western blot at 0.25 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- ACSL1 Antibody is supplied in PBS containing 0.02 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C,4 °C
-
储存方法
- ACSL1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
-
-
- ACSL1 (Acsl1) (Acyl-CoA Synthetase Long-Chain Family Member 1 (Acsl1))
-
别名
- ACSL1
-
背景
- ACSL1 Antibody: Long-chain acyl coenzyme A synthetase 1 (ACSL1) catalyzes the synthesis of acyl-CoA from long-chain fatty acids in an ATP-dependent manner. ACSL1 is a member of a family of long-chain acyl-CoA synthetases which differ in substrate preference, tissue expression, and subcellular localization. In mouse, ACSL1 is the major acyl-CoA enzyme in the heart, providing 60-90 % of heart ATP. Loss of ACSL1 either globally or in heart ventricles resulted in impaired fatty acid oxidation, activation of the mammalian target of rapamycin (mTOR), and cardiac hypertrophy.
-
分子量
-
Predicted: 41, 58, 77 kDa
Observed: 45, 47 kDa -
基因ID
- 2180
-
NCBI登录号
- NP_001986
-
UniProt
- P33121
-
途径
- Regulation of Lipid Metabolism by PPARalpha
抗原
-