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FLT3 抗体 (AA 340-390)

Name: FLT3 抗体 (AA 340-390)
Brand: antibodies-online
SKU: ABIN6991750
Availability: OutOfStock

This anti-FLT3 antibody is a 兔多克隆 antibody detecting FLT3 in WB, ELISA 和 IF. Suitable for 人和小鼠.

产品编号 ABIN6991750

发货至: 中国

Quick Overview for FLT3 抗体 (AA 340-390) (ABIN6991750)

抗原

See all FLT3 抗体

FLT3 (Fms-Related tyrosine Kinase 3 (FLT3))

适用

人, 小鼠

宿主

兔

克隆类型

多克隆

标记

This FLT3 antibody is un-conjugated

应用范围

Western Blotting (WB), ELISA, Immunofluorescence (IF)

Discover our top product FLT3 Primary Antibody

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AA 340-390

特异性

At least three isoforms of FLT3 are known to exist, this antibody will detect all isoforms.

纯化方法

FLT3 Antibody is affinity chromatography purified via peptide column.

免疫原

FLT3 antibody was raised against an 18 amino acid synthetic peptide near the center of human FLT3. The immunogen is located within amino acids 340 - 390 of FLT3.

亚型

IgG
anti-Fms-Related tyrosine Kinase 3 (FLT3) (AA 930-991) antibody
FLT3 适用: 人 ELISA, IHC 宿主: 小鼠 Monoclonal 7B7C3 unconjugated

anti-Fms-Related tyrosine Kinase 3 (FLT3) (AA 62-295) antibody
FLT3 适用: 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Fms-Related tyrosine Kinase 3 (FLT3) antibody
FLT3 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Fms-Related tyrosine Kinase 3 (FLT3) (AA 334-543) antibody
FLT3 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Fms-Related tyrosine Kinase 3 (FLT3) (AA 335-544) antibody
FLT3 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Fms-Related tyrosine Kinase 3 (FLT3) (AA 33-64) antibody
FLT3 适用: 人 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated

anti-Fms-Related tyrosine Kinase 3 (FLT3) (C-Term) antibody
FLT3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated

anti-Fms-Related tyrosine Kinase 3 (FLT3) antibody (FITC)
FLT3 适用: 人 FACS 宿主: 小鼠 Monoclonal BV10A4 FITC

anti-Fms-Related tyrosine Kinase 3 (FLT3) antibody (PE)
FLT3 适用: 人 FACS 宿主: 小鼠 Monoclonal BV10A4 PE

anti-Fms-Related tyrosine Kinase 3 (FLT3) (AA 650-750) antibody
FLT3 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

应用备注

FLT3 antibody can be used for detection of FLT3 by Western blot at 1 - 2 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in mouse samples and Immunofluorescence in human samples. All other applications and species not yet tested.

限制

仅限研究用
状态

Liquid

浓度

1 mg/mL

缓冲液

FLT3 Antibody is supplied in PBS containing 0.02 % sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C,4 °C

储存方法

FLT3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
抗原

FLT3 (Fms-Related tyrosine Kinase 3 (FLT3))

别名

FLT3

背景

FLT3 Antibody: FLT3 is a member of the class III receptor tyrosine kinase family and its internal tandem duplication (ITD) is preferentially seen in acute myeloid leukemia and myelodysplastic syndrome among various hematological malignancies. It is a membrane bound glycosylated protein that is expressed primarily in early hematopoietic progenitor cells. Upon binding its ligand FL, FLT3 activates multiple signaling pathways including the PI3K/Akt and Ras/MEK/MAPK pathways. In cells expressing FLT3-ITD, these pathways are constitutively on, resulting in abnormal cell growth and anti-apoptotic activity.

分子量

109 kDa

基因ID

2322

NCBI登录号

NP_004110

UniProt

P36888

途径

RTK signaling