TWEAK 抗体
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北京 101111
Quick Overview for TWEAK 抗体 (ABIN6991749)
抗原
See all TWEAK (TNFSF12) 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- TWEAK Antibody is Protein A-purified.
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免疫原
- Anti-TWEAK antibody was raised against recombinant human TWEAK protein.
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亚型
- IgG
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应用备注
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WB: 0.5-4 μ,g/mL, IHC: 5-10 μ,g/mL, IF: 20 μ,g/mL.
Antibody validated: Western Blot in human and mouse samples, Immunohistochemistry in human and mouse samples, Immunofluorescence in mouse samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- TWEAK Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- TWEAK antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- TWEAK (TNFSF12) (Tumor Necrosis Factor (Ligand) Superfamily, Member 12 (TNFSF12))
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别名
- TWEAK
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背景
- TWEAK Antibody: TNF-related weak inducer of apoptosis (TWEAK) is a member of the tumor necrosis factor superfamily (TNFSF) of structurally related cytokines. Like most other members of this family, TWEAK is a cell surface-associated type II transmembrane protein although a smaller, biologically active form can also be generated by cleavage near the cell membrane. TWEAK has multiple biological activities, including stimulation of cell growth and angiogenesis, induction of inflammatory cytokines, in addition to stimulation of apoptosis. The TWEAK signal transduction pathway has not been well established but it appears to signal via TweakR/Fn14 in a manner similar to that described for other TNFSF members that bind receptors lacking death domains.
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分子量
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Predicted: 27 and 36 kD
Observed: 27 and 36 kD kDa -
基因ID
- 8742
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NCBI登录号
- NP_003800
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UniProt
- O43508
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途径
- Apoptosis
抗原
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