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BCAR3 抗体 (N-Term)

This anti-BCAR3 antibody is a 兔 多克隆 antibody detecting BCAR3 in WB, ELISA 和 IF. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6991737
发货至: 中国

Quick Overview for BCAR3 抗体 (N-Term) (ABIN6991737)

抗原

See all BCAR3 抗体
BCAR3 (Breast Cancer Anti-Estrogen Resistance 3 (BCAR3))

适用

  • 15
  • 5
  • 2
  • 1
人, 小鼠, 大鼠

宿主

  • 14
  • 3
  • 1

克隆类型

  • 15
  • 3
多克隆

标记

  • 18
This BCAR3 antibody is un-conjugated

应用范围

  • 18
  • 11
  • 7
  • 7
  • 6
  • 5
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA, Immunofluorescence (IF)
  • 抗原表位

    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 30-80, N-Term

    特异性

    At least four isoforms of BCAR3 are known to exist, this antibody will only recognize the largest isoform. BCAR3 antibody is predicted to not cross-react with other BCAR proteins.

    纯化方法

    BCAR3 Antibody is affinity chromatography purified via peptide column.

    免疫原

    BCAR3 antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human BCAR3. The immunogen is located within amino acids 30 - 80 of BCAR3.

    亚型

    IgG
  • 应用备注

    BCAR3 antibody can be used for detection of BCAR3 by Western blot at 1 - 2 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    BCAR3 Antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,4 °C

    储存方法

    BCAR3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原

    BCAR3 (Breast Cancer Anti-Estrogen Resistance 3 (BCAR3))

    别名

    BCAR3

    背景

    BCAR3 Antibody: Breast cancer anti-estrogen resistance 3 (BCAR3) was identified in the search for genes involved in the development of estrogen resistance. It contains a putative src homology 2 (SH2) domain and is partly homologous to the cell division cycle protein CDC48. BCAR3 is a binding partner with Cas, an adapter molecule that plays a role in cell proliferation, survival, cell adhesion, and mobility. BCAR3 functions synergistically with Cas to enhance Src activation and promote cell migration, and has been suggested to regulate Cas/Src association, Src kinase activity, and breast cancer adhesion signaling.

    分子量

    91 kDa

    基因ID

    8412

    NCBI登录号

    NP_003558

    UniProt

    O75815
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