BCAR3 抗体 (N-Term)
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Quick Overview for BCAR3 抗体 (N-Term) (ABIN6991737)
抗原
See all BCAR3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 30-80, N-Term
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特异性
- At least four isoforms of BCAR3 are known to exist, this antibody will only recognize the largest isoform. BCAR3 antibody is predicted to not cross-react with other BCAR proteins.
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纯化方法
- BCAR3 Antibody is affinity chromatography purified via peptide column.
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免疫原
- BCAR3 antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human BCAR3. The immunogen is located within amino acids 30 - 80 of BCAR3.
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亚型
- IgG
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应用备注
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BCAR3 antibody can be used for detection of BCAR3 by Western blot at 1 - 2 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- BCAR3 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- BCAR3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- BCAR3 (Breast Cancer Anti-Estrogen Resistance 3 (BCAR3))
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别名
- BCAR3
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背景
- BCAR3 Antibody: Breast cancer anti-estrogen resistance 3 (BCAR3) was identified in the search for genes involved in the development of estrogen resistance. It contains a putative src homology 2 (SH2) domain and is partly homologous to the cell division cycle protein CDC48. BCAR3 is a binding partner with Cas, an adapter molecule that plays a role in cell proliferation, survival, cell adhesion, and mobility. BCAR3 functions synergistically with Cas to enhance Src activation and promote cell migration, and has been suggested to regulate Cas/Src association, Src kinase activity, and breast cancer adhesion signaling.
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分子量
- 91 kDa
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基因ID
- 8412
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NCBI登录号
- NP_003558
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UniProt
- O75815
抗原
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