TFEB 抗体 (C-Term)
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Quick Overview for TFEB 抗体 (C-Term) (ABIN6991678)
抗原
See all TFEB 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 390-440, C-Term
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特异性
- TFEB antibody is human specific. At least three isoforms of TFEB are known to exist.
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纯化方法
- TFEB antibody is affinity chromatography purified via peptide column.
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免疫原
- Rabbit polyclonal TFEB antibody was raised against a 16 amino acid peptide near the carboxy terminus of human TFEB. The immunogen is located within amino acids 390 - 440 of TFEB.
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亚型
- IgG
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应用备注
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TFEB antibody can be used for detection of TFEB by immunohistochemistry at 2.5 μ,g/mL.
Antibody validated: Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- TFEB antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- TFEB antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- TFEB (Transcription Factor EB (TFEB))
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别名
- TFEB
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背景
- The Transcription factor EB (TFEB) is a member in the basic helix-loop-helix leucine zipper superfamily of transcription factors that is translocated in a subset of renal tumors (1,2). Recent studies have shown that lysosomal biogenesis is regulated by TFEB (3), which is in turn regulated by the mammalian target of rapamycin (mTOR) complex 1 (4). Other evidence suggests that TFEB coordinates the major steps of the autophagic pathway by driving the expression of autophagy and lysosomal genes (5).
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基因ID
- 7942
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NCBI登录号
- NP_009093
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UniProt
- P19484
抗原
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