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VKORC1 抗体 (N-Term)

This 兔 多克隆 antibody specifically detects VKORC1 in WB, ELISA, IF 和 IHC (p). It exhibits reactivity toward 人 和 小鼠.
产品编号 ABIN6991675
发货至: 中国
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Quick Overview for VKORC1 抗体 (N-Term) (ABIN6991675)

抗原

See all VKORC1 抗体
VKORC1 (Vitamin K Epoxide Reductase Complex, Subunit 1 (VKORC1))

适用

  • 17
  • 5
  • 4
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
人, 小鼠

宿主

  • 17

克隆类型

  • 17
多克隆

标记

  • 7
  • 3
  • 3
  • 2
  • 1
  • 1
This VKORC1 antibody is un-conjugated

应用范围

  • 13
  • 12
  • 12
  • 4
  • 3
  • 3
  • 3
  • 2
  • 1
Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 7
    • 4
    • 3
    • 2
    • 1
    N-Term

    纯化方法

    VKORC1 Antibody is affinity chromatography purified via peptide column.

    免疫原

    VKORC1 antibody was raised against a 15 amino acid synthetic peptide near the amino terminus of human VKORC1. The immunogen is located within the first 50 amino acids of VKORC1.

    亚型

    IgG
  • 应用备注

    VKORC1 antibody can be used for detection of VKORC1 by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 5 μ,g/mL.

    Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    VKORC1 Antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,4 °C

    储存方法

    VKORC1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原

    VKORC1 (Vitamin K Epoxide Reductase Complex, Subunit 1 (VKORC1))

    别名

    VKORC1

    背景

    VKORC1 Antibody: Vitamin K epoxide reductase complex subunit 1 (VKORC1) is the enzyme that is responsible for reducing vitamin K 2,3-epoxide to the enzymatically activated form which is essential for blood clotting. This enzymatically activated form of vitamin K is a reduced form required for the carboxylation of glutamic acid residues in some blood-clotting proteins. Fatal bleeding can be caused by vitamin K deficiency and by the vitamin K antagonist warfarin, and it is VKORC1 that is sensitive to warfarin. In humans, mutations in this gene can be associated with deficiencies in vitamin-K-dependent clotting factors and, in humans and rats, with warfarin resistance.

    基因ID

    79001

    NCBI登录号

    NP_076869

    UniProt

    Q9BQB6
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