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VKORC1 抗体 (N-Term)

VKORC1 适用: 人, 小鼠, 大鼠, Cow, 兔, 犬, 豚鼠, 马 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2789450
发货至: 中国
  • 抗原 See all VKORC1 抗体
    VKORC1 (Vitamin K Epoxide Reductase Complex, Subunit 1 (VKORC1))
    抗原表位
    • 8
    • 7
    • 5
    • 4
    • 2
    • 1
    N-Term
    适用
    人, 小鼠, 大鼠, Cow, 兔, 犬, 豚鼠, 马
    宿主
    • 22
    克隆类型
    • 22
    多克隆
    标记
    • 7
    • 4
    • 4
    • 3
    • 2
    • 2
    This VKORC1 antibody is un-conjugated
    应用范围
    • 18
    • 18
    • 16
    • 5
    • 3
    • 3
    • 3
    • 3
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    序列
    LHVKAARARD RDYRALCDVG TAISCSRVFS SRLPADTLGL CPDAAELPGV
    预测反应
    Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 86%, Rabbit: 100%, Rat: 86%
    产品特性
    This is a rabbit polyclonal antibody against VKORC1. It was validated on Western Blot.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N-terminal region of VKORC1
    Top Product
    Discover our top product VKORC1 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 92 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    VKORC1 (Vitamin K Epoxide Reductase Complex, Subunit 1 (VKORC1))
    别名
    VKORC1 (VKORC1 产品)
    别名
    MGC89620 antibody, BP1071 antibody, CG33544 antibody, Dmel\\CG33544 antibody, HDC06808 antibody, VKORC1 antibody, EDTP308 antibody, IMAGE3455200 antibody, MST134 antibody, MST576 antibody, VKCFD2 antibody, VKOR antibody, D7Wsu86e antibody, vitamin K epoxide reductase complex, subunit 1 antibody, vitamin K epoxide reductase complex subunit 1 antibody, Vitamin-K epoxide reductase antibody, VKORC1 antibody, vkorc1 antibody, Vkor antibody, Vkorc1 antibody
    背景
    Vitamin K is essential for blood clotting but must be enzymatically activated. This enzymatically activated form of vitamin K is a reduced form required for the carboxylation of glutamic acid residues in some blood-clotting proteins. The product of this gene encodes the enzyme that is responsible for reducing vitamin K 2,3-epoxide to the enzymatically activated form. Fatal bleeding can be caused by vitamin K deficiency and by the vitamin K antagonist warfarin, and it is the product of this gene that is sensitive to warfarin. In humans, mutations in this gene can be associated with deficiencies in vitamin-K-dependent clotting factors and, in humans and rats, with warfarin resistance. Two pseudogenes have been identified on chromosome 1 and the X chromosome. Two alternatively spliced transcripts encoding different isoforms have been described.
    Alias Symbols: EDTP308, FLJ00289, IMAGE3455200, MGC2694, MST134, MST576, VKCFD2, VKOR
    Protein Interaction Partner: UBC, ILK, ZMYM6NB, TMEM242, SNORA12, TMEM256, ZCCHC24, METTL7B, SPTSSA, VKORC1L1, CCDC167, CCDC12, TMEM45B, KCNK17, JAGN1, SERP1, PPA2, TRAM1, TREX1, YIF1A, EBP, ARL6IP5, PROCR, IFITM3, ATP6AP2, BCAP31, PDIA6, HDAC6, HOMER2, VAPB, CLDN10, DPM2, REEP5, TF,
    Protein Size: 92
    分子量
    10 kDa
    基因ID
    79001
    NCBI登录号
    NM_206824, NP_996560
    UniProt
    Q9BQB6
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