HHATL 抗体 (N-Term)
This anti-HHATL antibody is a 兔 多克隆 antibody detecting HHATL in WB, ELISA, IHC (p) 和 IF. Suitable for 人, 小鼠 和 大鼠.
Quick Overview for HHATL 抗体 (N-Term) (ABIN6991671)
抗原
See all HHATL 抗体
HHATL
(Hedgehog Acyltransferase-Like (HHATL))
适用
人, 小鼠, 大鼠
宿主
兔
克隆类型
多克隆
标记
This HHATL antibody is un-conjugated
应用范围
Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
-
-
抗原表位
- N-Term
-
纯化方法
- HHATL Antibody is affinity chromatography purified via peptide column.
-
免疫原
- HHATL antibody was raised against a 19 amino acid synthetic peptide near the amino terminus of human HHATL. The immunogen is located within the first 50 amino acids of HHATL.
-
亚型
- IgG
-
-
anti-Hedgehog Acyltransferase-Like (HHATL) (N-Term) antibody
HHATL 适用: 人, 小鼠, 大鼠 WB, IHC (p), IF, EIA 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
HHATL antibody can be used for detection of HHATL by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 2.5 μ,g/mL.
Antibody validated: Western Blot in mouse samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- HHATL Antibody is supplied in PBS containing 0.02 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C,4 °C
-
储存方法
- HHATL antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
-
-
- HHATL (Hedgehog Acyltransferase-Like (HHATL))
-
别名
- HHATL
-
背景
- HHATL Antibody: The Protein-cysteine N-palmitoyltransferase HHAT-like protein (HHATL), also known at the mammalian glycerol uptake/transporter 1 (Gup1) is a homolog of the S. cerevisiae Gup1. It is an endoplasmic reticulum (ER) membrane protein that co-localizes with the mammalian hedgehog acyltransferse Skn and interferes with its N-terminal palmitoylation of Sonic hedgehog (SHH), suggesting that HHATL acts as a negative regulator for N-terminal palmitoylation of SHH. HHATL is highly expressed in normal skin, but becomes down-regulated in skin squamous cell carcinoma, suggesting it may play a role in its development.
-
基因ID
- 57467
-
NCBI登录号
- NP_065758
-
UniProt
- Q9HCP6
-
途径
- Hedgehog Signaling
抗原
-
You are here:
