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HHATL 抗体 (N-Term)

This anti-HHATL antibody is a 兔 多克隆 antibody detecting HHATL in WB, ELISA, IHC (p) 和 IF. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6991671
发货至: 中国

Quick Overview for HHATL 抗体 (N-Term) (ABIN6991671)

抗原

See all HHATL 抗体
HHATL (Hedgehog Acyltransferase-Like (HHATL))

适用

人, 小鼠, 大鼠

宿主

  • 16
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克隆类型

  • 16
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多克隆

标记

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This HHATL antibody is un-conjugated

应用范围

  • 16
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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
  • 抗原表位

    • 15
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    N-Term

    纯化方法

    HHATL Antibody is affinity chromatography purified via peptide column.

    免疫原

    HHATL antibody was raised against a 19 amino acid synthetic peptide near the amino terminus of human HHATL. The immunogen is located within the first 50 amino acids of HHATL.

    亚型

    IgG
  • 应用备注

    HHATL antibody can be used for detection of HHATL by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 2.5 μ,g/mL.

    Antibody validated: Western Blot in mouse samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    HHATL Antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,4 °C

    储存方法

    HHATL antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原

    HHATL (Hedgehog Acyltransferase-Like (HHATL))

    别名

    HHATL

    背景

    HHATL Antibody: The Protein-cysteine N-palmitoyltransferase HHAT-like protein (HHATL), also known at the mammalian glycerol uptake/transporter 1 (Gup1) is a homolog of the S. cerevisiae Gup1. It is an endoplasmic reticulum (ER) membrane protein that co-localizes with the mammalian hedgehog acyltransferse Skn and interferes with its N-terminal palmitoylation of Sonic hedgehog (SHH), suggesting that HHATL acts as a negative regulator for N-terminal palmitoylation of SHH. HHATL is highly expressed in normal skin, but becomes down-regulated in skin squamous cell carcinoma, suggesting it may play a role in its development.

    基因ID

    57467

    NCBI登录号

    NP_065758

    UniProt

    Q9HCP6

    途径

    Hedgehog Signaling
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